دورية أكاديمية
Situation of multidrug-resistant pulmonary tuberculosis in Alexandria governorate from July 2008 to December 2012
| العنوان: | Situation of multidrug-resistant pulmonary tuberculosis in Alexandria governorate from July 2008 to December 2012 |
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| المؤلفون: | Osama I. Mohammad, Ali A. Okab, Mostafa E. Zaki |
| المصدر: | The Egyptian Journal of Bronchology, Vol 10, Iss 1, Pp 64-68 (2016) |
| بيانات النشر: | SpringerOpen, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Diseases of the respiratory system LCC:Medical emergencies. Critical care. Intensive care. First aid |
| مصطلحات موضوعية: | multidrug resistant, pulmonary, tuberculosis, Diseases of the respiratory system, RC705-779, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9 |
| الوصف: | Abstract Aim The aim of this study was to estimate the prevalence, possible risk factors, patterns of resistance, and fate of multidrug-resistant pulmonary tuberculosis (MDR-TB) in Alexandria governorate as a representative part of Egypt during the period between July 2008 and December 2012. Patients and methods This retrospective study included all patients with pulmonary TB that was recorded in Alexandria governorate during the period between July 2008 (the time that MDR ward was held in Alexandria) and December 2012. They were divided into two groups: group I included patients with pulmonary TB that was recorded in Alexandria governorate (1893 cases), and group II included patients with pulmonary TB who were admitted in El-Maamoura Chest Hospital (509 cases). They were subdivided into two subgroups: group IIa included patients with MDR pulmonary TB (82 cases), and group IIb included patients with pulmonary TB not categorized as MDR-TB (427 cases). Results All patients with MDR-TB had acquired resistance. MDR-TB was more common in the male population, diabetic patients, and those with chronic chest disease. The effect of treatment of MDR-TB cases was as follows: cured patients, 49 (59.8%); patients under treatment, 10 (12.2%); treatment failure, four cases (4.9%); deceased patients, 10 (12.2%); and defaulters, nine (10.9%). The overall total prevalence rate of MDR-TB in Alexandria governorate from 2008 to 2012 was 4.3%. Conclusion There was a decreasing trend of MDR-TB cases. History of anti-TB treatment is the strongest independent predictor of MDR-TB. The highest figures of resistance in the MDR group besides isoniazide and rifampicin were for streptomycin, whereas the lowest resistance was for ethambutol. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1687-8426 2314-8551 |
| Relation: | http://link.springer.com/article/10.4103/1687-8426.176792; https://doaj.org/toc/1687-8426; https://doaj.org/toc/2314-8551 |
| DOI: | 10.4103/1687-8426.176792 |
| URL الوصول: | https://doaj.org/article/1b3d73f4cfa143e88da7edcbc67d6f7f |
| رقم الأكسشن: | edsdoj.1b3d73f4cfa143e88da7edcbc67d6f7f |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 16878426 23148551 |
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| DOI: | 10.4103/1687-8426.176792 |