دورية أكاديمية
P13 Evaluation of the effect of the roots of Beta vulgaris (Chenopodiaceae) juice on adults subjects with grade 1 hypertension under dietary regime
| العنوان: | P13 Evaluation of the effect of the roots of Beta vulgaris (Chenopodiaceae) juice on adults subjects with grade 1 hypertension under dietary regime |
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| المؤلفون: | F M P Obono, Hamadou Ba, L V Soppo, B H P Betote, M F Benga, F J S Maniepi, M J Nko'O, F Ngolsou, N M Nyangono, Nnanga Nga, S Kingue, J Ze Minkande |
| المصدر: | Journal Africain de Technologie Pharmaceutique et Biopharmacie, Vol 2, Iss 3 (2023) |
| بيانات النشر: | Société Ouest Africaine de Pharmacie Galénique et Industrielle, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Pharmaceutical industry |
| مصطلحات موضوعية: | Beetroot juice, Hypertension, blood pressure, Pharmaceutical industry, HD9665-9675 |
| الوصف: | Introduction: Lifestyle modification like increasing fruits/vegetables consumption is one of the key approaches in treating arterial hypertension: a major risk factor for mortality worldwide. Beta vulgaris (beetroot) and other vegetables consume frequently could be a rich source of inorganic nitrates, which will be converted to nitric oxide. Objective: To evaluate the effect of the roots of Beta vulgaris (Chenopodiaceae) juice on adults’ subjects with grade 1 hypertension under dietary regime. Methodology: Beetroot was obtained at the local market and decontaminated. Beetroot juice (BJ) was extracted and freeze till utilization. Recruitment was hospital-based, were included all adult subjects of both sexes, with grade 1 hypertensive according to the Joint National Committee 7, not subject to pharmacological treatment, non-gravid women. A single-blinded, randomized, placebo-controlled trial was performed during 4 weeks. Volunteers were randomized to receive either 250 mL of BJ or water (placebo) during 02 weeks and blood pressure (BP) registered in triplicates at baseline, 3 h, at 24 h. BP was recorded daily at home during trial, a week before, and after receiving BJ using an automatic BP machine. Blood and urine nitrates were assessed at baseline and 3 h after drinking juice. Results: A total of 14 subjects participated in the trial including 9 women and 5 men. An overall non-significant decrease in BP of 4.5/0.41 mmHg (decrease of 5.62/2.25 mmHg at H3 [p-value = 0.2427/0.3385], and decrease of 1.4 mmHg in systolic blood pressure at the 24th hour [p-value = 0.4150]) in the intervention group compared to the control group respectively for systolic and diastolic blood pressure of the intervention was observed [p-value = 0.1255/0.1612]. No change in blood and urine nitrite was registered. Conclusion: Beetroot juice decrease non-significantly blood pressure. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English French |
| تدمد: | 2756-7362 |
| Relation: | https://soapgi-jatpb.org/index.php/jatpb/article/view/143; https://doaj.org/toc/2756-7362 |
| DOI: | 10.57220/jatpb.v2i3.143 |
| URL الوصول: | https://doaj.org/article/1b66294c99e742c6872611430f82a540 |
| رقم الأكسشن: | edsdoj.1b66294c99e742c6872611430f82a540 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 27567362 |
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| DOI: | 10.57220/jatpb.v2i3.143 |