دورية أكاديمية
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Micro-Computed Tomography Soft Tissue Biological Specimens Image Data Visualization

التفاصيل البيبلوغرافية
العنوان: Micro-Computed Tomography Soft Tissue Biological Specimens Image Data Visualization
المؤلفون: Branislav Gaspar, Jana Mrzilkova, Jiri Hozman, Petr Zach, Anastasiya Lahutsina, Alexandra Morozova, Giulia Guarnieri, Jitka Riedlova
المصدر: Applied Sciences, Vol 12, Iss 10, p 4918 (2022)
بيانات النشر: MDPI AG, 2022.
سنة النشر: 2022
المجموعة: LCC:Technology
LCC:Engineering (General). Civil engineering (General)
LCC:Biology (General)
LCC:Physics
LCC:Chemistry
مصطلحات موضوعية: micro-CT, transfer function, look-up-table, soft tissue, CT number, Hounsfield unit, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999
الوصف: Visualization of soft tissues in microCT scanning using X-rays is still a complicated matter. There is no simple tool or methodology on how to set up an optimal look-up-table while respecting the type of soft tissue. A partial solution may be the use of a contrast agent. However, this must be accompanied by an appropriate look-up-table setting that respects the relationship between the soft tissue type and the Hounsfield units. The main aim of the study is to determine experimentally derived look-up-tables and relevant values of the Hounsfield units based on the statistical correlation analysis. These values were obtained from the liver and kidneys of 24 mice in solutions of ethanol as the centroid value of the opacity look-up-table area under this graph. Samples and phantom were scanned by a Bruker SkyScan 1275 micro-CT and Phywe XR 4.0 and processed using CTvox and ORS Dragonfly software. To reconstruct the micro-CT projections, NRecon software was used. The main finding of the study is that there is a statistically significant relationship between the centroid of the area under the look-up-table curve and the number of days for which the animal sample was stored in an ethanol solution. H1 of the first hypothesis, i.e. that suggested the Spearman’s correlation coefficient does not equal zero (r1 ≠ 0) regarding this relationship was confirmed. On the other hand, there is no statistically significant relationship between the centroid of the area under the look-up-table curve and the concentration of the ethanol solution. In this case, H1 of the second hypothesis, i.e. that the Spearman’s correlation coefficient does not equal zero (r2 ≠ 0) regarding this relationship was not confirmed. Spearman’s correlation coefficients were −0.27 for the concentration and −0.87 for the number of days stored in ethanol solution in the case of the livers of 13 mice and 0.06 for the concentration and 0.94 for the number of days stored in ethanol solution in the case of kidneys of 11 mice.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2076-3417
79499910
Relation: https://www.mdpi.com/2076-3417/12/10/4918; https://doaj.org/toc/2076-3417
DOI: 10.3390/app12104918
URL الوصول: https://doaj.org/article/d1b79499910341a3a6194f4502020fdc
رقم الأكسشن: edsdoj.1b79499910341a3a6194f4502020fdc
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20763417
79499910
DOI:10.3390/app12104918