دورية أكاديمية
Management of a complicated case of liver transplant patient with multiple alloantibodies
| العنوان: | Management of a complicated case of liver transplant patient with multiple alloantibodies |
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| المؤلفون: | Nitin Agarwal, Prashant Pandey, Mukesh Kumar, Anurag Kumar |
| المصدر: | Global Journal of Transfusion Medicine, Vol 4, Iss 1, Pp 90-92 (2019) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Diseases of the blood and blood-forming organs |
| مصطلحات موضوعية: | Adsorption, alloimmunization, antibody identification, anti-C, anti-e, elution, multiple alloantibodies, Diseases of the blood and blood-forming organs, RC633-647.5 |
| الوصف: | The focus of transfusion services is now shifting toward the prevention of alloimmunization and delayed hemolysis, especially in multi-transfused patients. Here, we present a complex case of a multitransfused chronic liver disease patient, alloimmunized with multiple Rh antibodies posted for a liver transplant. Our blood bank successfully managed this patient and was able to supply the required blood components on time to save his life. A 28-year-old male patient was admitted to our hospital for the liver transplant. Blood bank could not find compatible blood units for the patient. The patient antibody screen was positive and the pattern was suggestive of anti-E antibody, but few other antibodies such as C, K, Fyb, and N could not be ruled out. Eluate showed the same result on antibody screening. The patient serum was alloadsorbed with “rr” blood using conventional tube technique. Adsorbed patient serum showed the pattern of hidden anti-C and we confirmed that patient serum contained anti-E and anti-C antibodies. As “e” antigen is a high prevalence antigen, we could not find an e negative unit and only C negative unit could be provided to the patient without any untoward incidence. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2468-8398 2455-8893 |
| Relation: | http://www.gjtmonline.com/article.asp?issn=2468-8398;year=2019;volume=4;issue=1;spage=90;epage=92;aulast=Agarwal; https://doaj.org/toc/2468-8398; https://doaj.org/toc/2455-8893 |
| DOI: | 10.4103/GJTM.GJTM_49_18 |
| URL الوصول: | https://doaj.org/article/1c1b52d2b18a48279778c762f86aeb5a |
| رقم الأكسشن: | edsdoj.1c1b52d2b18a48279778c762f86aeb5a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 24688398 24558893 |
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| DOI: | 10.4103/GJTM.GJTM_49_18 |