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Covalent Organic Frameworks as Nanocarriers for Improved Delivery of Chemotherapeutic Agents

التفاصيل البيبلوغرافية
العنوان: Covalent Organic Frameworks as Nanocarriers for Improved Delivery of Chemotherapeutic Agents
المؤلفون: Weiming Liu, Xinyu Ma, Shuayb Mohamed Kheyr, Anjie Dong, Jianhua Zhang
المصدر: Materials, Vol 15, Iss 20, p 7215 (2022)
بيانات النشر: MDPI AG, 2022.
سنة النشر: 2022
المجموعة: LCC:Technology
LCC:Electrical engineering. Electronics. Nuclear engineering
LCC:Engineering (General). Civil engineering (General)
LCC:Microscopy
LCC:Descriptive and experimental mechanics
مصطلحات موضوعية: covalent organic frameworks, nanocarriers, drug delivery, nanomedicine, Technology, Electrical engineering. Electronics. Nuclear engineering, TK1-9971, Engineering (General). Civil engineering (General), TA1-2040, Microscopy, QH201-278.5, Descriptive and experimental mechanics, QC120-168.85
الوصف: Cancer has become one of the main causes of death worldwide. Chemotherapy as one of the main therapy modalities is very unsatisfactory. The various nanocarriers have brought new opportunities for effective tumor treatment. However, most of the current nanocarriers still suffer from low efficiency and confront significant challenges in overcoming multiple biological barriers. Compared with conventional nanocarriers, covalent organic frameworks (COFs) with unique and attractive features exhibited great potential to serve as a promising platform for anticancer drug delivery. In this review, we first summarize the strategies and challenges of nanocarriers for cancer chemotherapy and then highlight the recent advances in COF-based nanocarriers for improved delivery of chemotherapeutic agents. Finally, the challenges remaining for COF-based nanocarriers for clinical applications are outlined.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1996-1944
Relation: https://www.mdpi.com/1996-1944/15/20/7215; https://doaj.org/toc/1996-1944
DOI: 10.3390/ma15207215
URL الوصول: https://doaj.org/article/1c964d646c6d4541a3286650beb986bf
رقم الأكسشن: edsdoj.1c964d646c6d4541a3286650beb986bf
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19961944
DOI:10.3390/ma15207215