دورية أكاديمية
Synthesis and Antimicrobial Analysis of High Surface Area Strontium-Substituted Calcium Phosphate Nanostructures for Bone Regeneration
| العنوان: | Synthesis and Antimicrobial Analysis of High Surface Area Strontium-Substituted Calcium Phosphate Nanostructures for Bone Regeneration |
|---|---|
| المؤلفون: | Aneela Anwar, Qudsia Kanwal, Ayesha Sadiqa, Tabassam Razaq, Iqra Haider Khan, Arshad Javaid, Safia Khan, ElSayed Tag-Eldin, Mohamed Ouladsmane |
| المصدر: | International Journal of Molecular Sciences, Vol 24, Iss 19, p 14527 (2023) |
| بيانات النشر: | MDPI AG, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | antimicrobial, bioceramics, bone regeneration, calcium phosphates, Macrophomina phaseolina, nanopowder, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | Continuous microwave-assisted flow synthesis has been used as a simple, more efficient, and low-cost route to fabricate a range of nanosized (2+ ion source) and diammonium hydrogen phosphate at pH 10 with a time duration of 5 min. The morphological characterization of the obtained powder has been carried out by employing techniques such as transmission electron microscopy, X-ray diffraction, and Brunauer–Emmett–Teller surface area analysis. The chemical structural analysis to evaluate the surface properties was made by using X-ray photoelectron spectroscopy. Zeta potential analysis was performed to evaluate the colloidal stability of the particles. Antimicrobial studies were performed for all the compositions using four bacterial strains and an opportunistic human fungal pathogen Macrophomina phaseolina. It was found that the nanoproduct with high strontium content (15 wt% of strontium) showed pronounced antibacterial potential against M. luteus while it completely arrested the fungal growth after 48 h by all of its concentrations. Thus the synthesis strategy described herein facilitated the rapid production of nanosized Sr-substituted CaPs with excellent biological performance suitable for a bone replacement application. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/24/19/14527; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms241914527 |
| URL الوصول: | https://doaj.org/article/1d4b98c27c7744d292f3ef39a2a45020 |
| رقم الأكسشن: | edsdoj.1d4b98c27c7744d292f3ef39a2a45020 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
|---|---|
| DOI: | 10.3390/ijms241914527 |