دورية أكاديمية
Kidney tissue elastography and interstitial fibrosis observed in kidney biopsy
| العنوان: | Kidney tissue elastography and interstitial fibrosis observed in kidney biopsy |
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| المؤلفون: | Mehmet Sami Islamoglu, Sibel Gulcicek, Nurhan Seyahi |
| المصدر: | Renal Failure, Vol 44, Iss 1, Pp 314-319 (2022) |
| بيانات النشر: | Taylor & Francis Group, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: | elastography interstitial fibrosis, kidney kidney biopsy, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | Introduction Kidney interstitial fibrosis is an important risk factor for the progression of chronic kidney disease. Kidney elastography is a noninvasive imaging modality that might be used to assess tissue fibrosis. In this study, we aimed to investigate the relationship between tissue stiffness detected in kidney elastography and interstitial fibrosis observed in kidney biopsy. Materials and methods Patients who were hospitalized in a tertiary care university hospital with a kidney biopsy indication were included in this study. In all patients, the transverse and sagittal elastography measurements were made using a sonoelastography device before the biopsy. The total histological score was calculated. Results Fifty-seven native kidney patients with proteinuria were included in the study. Patients were divided into two groups according to the presence (n = 6) and absence of fibrosis (n = 51) as detected by kidney biopsy. A significant correlation was found between the presence of fibrosis detected by biopsy and elastography outcomes (p = .046, r = .192). A significant correlation was found between the urea and creatinine levels and transverse elastography measurements (p = .036, r = .240). No correlation was observed between the transverse elastography measurements and total histological score consisting of glomerular, vascular, and tubular scores (r = .006, p = .967) Conclusion The findings of our study suggest a significant relationship between the elastography measurements and interstitial fibrosis. Because of the high negative predictive value (91%), we suggest that elastography should mainly be used as an exclusion test for the presence of fibrosis. We also believe that elastography may be useful to evaluate the fibrosis status in kidney diseases. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0886-022X 1525-6049 0886022X |
| Relation: | https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049 |
| DOI: | 10.1080/0886022X.2022.2035763 |
| URL الوصول: | https://doaj.org/article/1dbf685e481d428e975b4f93e901873f |
| رقم الأكسشن: | edsdoj.1dbf685e481d428e975b4f93e901873f |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 0886022X 15256049 |
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| DOI: | 10.1080/0886022X.2022.2035763 |