دورية أكاديمية
Association between suicidal risks and medication-overuse headache in chronic migraine: a cross-sectional study
| العنوان: | Association between suicidal risks and medication-overuse headache in chronic migraine: a cross-sectional study |
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| المؤلفون: | Yen-Feng Wang, Chia-Chun Yu, Ai Seon Kuan, Shih-Pin Chen, Shuu-Jiun Wang |
| المصدر: | The Journal of Headache and Pain, Vol 22, Iss 1, Pp 1-8 (2021) |
| بيانات النشر: | BMC, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | Migraine, Substance dependence, Medication-overuse headache, Suicide, Medicine |
| الوصف: | Abstract Background Behaviors of substance dependence are common among patients with medication-overuse headache (MOH). Whether MOH, like other substance use disorders, is associated with an increased risk for suicide is unknown. Methods In this cross-sectional study, newly diagnosed chronic migraine (CM) patients with or without coexisting MOH were enrolled prospectively. Headache diagnoses were made through face-to-face interviews by headache specialists, and a specifically designed questionnaire was used to collect demographics, headache profiles, Migraine Disability Assessment, Hospital Anxiety and Depression Scale, Pittsburgh Sleep Quality Index, etc. Suicidal ideation and prior suicide attempt were specifically questioned. Results In total, 603 CM patients (485F/118M, mean age 42.03 ± 12.18 years) were recruited, including 320 with MOH (257F/63M, mean age 42.8 ± 11.7 years) (53.1%), and 214 (35.5%) and 81 (13.4%) had suicidal ideation and prior suicide attempt, respectively. Among CM patients, the presence of MOH increased the risks of suicidal ideation (odds ratio [OR] = 1.75 [95% CI = 1.20–2.56], p = 0.004) and prior suicide attempt (OR = 1.88 [1.09–3.24], p = 0.024), after controlling for demographics, headache profile, disabilities, symptoms of anxiety and depression, and sleep quality. Conclusions In CM patients, MOH is associated with an increased risk for suicidal ideation and prior suicide attempt, which deserves attention for clinicians taking care of headache patients. However, further studies are needed to determine the causal relationship, as well as the underlying pathophysiology. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1129-2369 1129-2377 |
| Relation: | https://doaj.org/toc/1129-2369; https://doaj.org/toc/1129-2377 |
| DOI: | 10.1186/s10194-021-01248-0 |
| URL الوصول: | https://doaj.org/article/1deb92e390a541d49e179c5ffdd91111 |
| رقم الأكسشن: | edsdoj.1deb92e390a541d49e179c5ffdd91111 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 11292369 11292377 |
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| DOI: | 10.1186/s10194-021-01248-0 |