دورية أكاديمية
Evaluation of the knockdown resistance locus (kdr) in Anopheles stephensi (Diptera: Culicidae) in southeastern Iran
| العنوان: | Evaluation of the knockdown resistance locus (kdr) in Anopheles stephensi (Diptera: Culicidae) in southeastern Iran |
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| المؤلفون: | Ramtin Hajibeygi, Seyed Zia Hejripour, Nader Taghavi, Hamzeh Shahali, Saeed Zarei, Majid Nouri, Hadi Mirahmadi, Seyed Mahdi Tabatabaie, Rahmat Solgi, Mohammad Darvishi |
| المصدر: | Journal of Vector Borne Diseases, Vol 60, Iss 4, Pp 444-448 (2023) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | insecticide, anopheles stephensi, permethrin, ddt, iran, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Background & objectives: The resistance to insecticide among Anopheles stephensi population due to insecticide selection pressure has been previously reported from Iran. The current study was performed to evaluate the susceptibility of different insecticide reagents against An. stephensi by bioassay and molecular methods in Saravan County, a malaria-endemic area in southeastern Iran. Methods: An. stephensi mosquitoes were collected from different larval habitats in Saravan City, southeastern Iran in 2022. At first, the susceptibility of collected samples for DDT, permethrin, and deltamethrin were evaluated by bioassay test. The collected mosquitoes were then evaluated for the presence of different kdr mutations. Results: Insecticide susceptibility tests were conducted on the field population of An. stephensi from Saravan, revealing its potential resistance to pyrethroids and DDT. Of the 150 An. stephensi samples, 4 % carried the kdr L1014F mutation as heterozygous and the rest of them were homozygous L1014 wild type. Interpretation & conclusion: The current study revealed the presence of L1014F mutation for the first time in Iran. So, further monitoring of kdr mutations in the VGSC gene and resistance phenotypes should be performed. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0972-9062 53075552 |
| Relation: | http://www.jvbd.org/article.asp?issn=0972-9062;year=2023;volume=60;issue=4;spage=444;epage=448;aulast=Hajibeygi; https://doaj.org/toc/0972-9062 |
| DOI: | 10.4103/0972-9062.383648 |
| URL الوصول: | https://doaj.org/article/1e6e848843ec4a39ba0aa53075552c13 |
| رقم الأكسشن: | edsdoj.1e6e848843ec4a39ba0aa53075552c13 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 09729062 53075552 |
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| DOI: | 10.4103/0972-9062.383648 |