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The prognostic value of De Ritis (AST/ALT) ratio in patients after surgery for urothelial carcinoma: a systematic review and meta-analysis

التفاصيل البيبلوغرافية
العنوان: The prognostic value of De Ritis (AST/ALT) ratio in patients after surgery for urothelial carcinoma: a systematic review and meta-analysis
المؤلفون: Xu Hu, Wei-Xiao Yang, Yan Wang, Yan-Xiang Shao, San-Chao Xiong, Xiang Li
المصدر: Cancer Cell International, Vol 20, Iss 1, Pp 1-8 (2020)
بيانات النشر: BMC, 2020.
سنة النشر: 2020
المجموعة: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
LCC:Cytology
مصطلحات موضوعية: De Ritis ratio, Urothelial carcinoma, Surgery, Prognosis, Meta-analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671
الوصف: Abstract Background Recently, the De Ritis (AST/ALT) ratio has been considered as a prognostic biomarker for various malignancies. We conducted this systematic review and meta-analysis to explore the prognostic value of preoperative De Ritis ratio in patients after surgery for urothelial carcinoma. Methods We searched the online database Embase, PubMed and Cochrane Library up to October 2019. The hazard ratio (HR) and 95% confidence interval (CI) were extracted from the studies. Results A total of 8 studies incorporating 3949 patients were included in the quantitative synthesis. We observed that elevated preoperative De Ritis ratio is associated with inferior OS (HR = 1.97; 95% CI 1.70–2.28; P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1475-2867
Relation: https://doaj.org/toc/1475-2867
DOI: 10.1186/s12935-020-1125-2
URL الوصول: https://doaj.org/article/1eae512847f94e4ea3409edff76fc454
رقم الأكسشن: edsdoj.1eae512847f94e4ea3409edff76fc454
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14752867
DOI:10.1186/s12935-020-1125-2