دورية أكاديمية
The prognostic value of De Ritis (AST/ALT) ratio in patients after surgery for urothelial carcinoma: a systematic review and meta-analysis
العنوان: | The prognostic value of De Ritis (AST/ALT) ratio in patients after surgery for urothelial carcinoma: a systematic review and meta-analysis |
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المؤلفون: | Xu Hu, Wei-Xiao Yang, Yan Wang, Yan-Xiang Shao, San-Chao Xiong, Xiang Li |
المصدر: | Cancer Cell International, Vol 20, Iss 1, Pp 1-8 (2020) |
بيانات النشر: | BMC, 2020. |
سنة النشر: | 2020 |
المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens LCC:Cytology |
مصطلحات موضوعية: | De Ritis ratio, Urothelial carcinoma, Surgery, Prognosis, Meta-analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671 |
الوصف: | Abstract Background Recently, the De Ritis (AST/ALT) ratio has been considered as a prognostic biomarker for various malignancies. We conducted this systematic review and meta-analysis to explore the prognostic value of preoperative De Ritis ratio in patients after surgery for urothelial carcinoma. Methods We searched the online database Embase, PubMed and Cochrane Library up to October 2019. The hazard ratio (HR) and 95% confidence interval (CI) were extracted from the studies. Results A total of 8 studies incorporating 3949 patients were included in the quantitative synthesis. We observed that elevated preoperative De Ritis ratio is associated with inferior OS (HR = 1.97; 95% CI 1.70–2.28; P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1475-2867 |
Relation: | https://doaj.org/toc/1475-2867 |
DOI: | 10.1186/s12935-020-1125-2 |
URL الوصول: | https://doaj.org/article/1eae512847f94e4ea3409edff76fc454 |
رقم الأكسشن: | edsdoj.1eae512847f94e4ea3409edff76fc454 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14752867 |
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DOI: | 10.1186/s12935-020-1125-2 |