دورية أكاديمية
Combining Biocompatible and Biodegradable Scaffolds and Cold Atmospheric Plasma for Chronic Wound Regeneration
| العنوان: | Combining Biocompatible and Biodegradable Scaffolds and Cold Atmospheric Plasma for Chronic Wound Regeneration |
|---|---|
| المؤلفون: | Steffen Emmert, Sven Pantermehl, Aenne Foth, Janine Waletzko-Hellwig, Georg Hellwig, Rainer Bader, Sabine Illner, Niels Grabow, Sander Bekeschus, Klaus-Dieter Weltmann, Ole Jung, Lars Boeckmann |
| المصدر: | International Journal of Molecular Sciences, Vol 22, Iss 17, p 9199 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | skin regeneration, wound healing, plasma medicine, disinfection, blood flow enhancement, electrospinning, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | Skin regeneration is a quite complex process. Epidermal differentiation alone takes about 30 days and is highly regulated. Wounds, especially chronic wounds, affect 2% to 3% of the elderly population and comprise a heterogeneous group of diseases. The prevailing reasons to develop skin wounds include venous and/or arterial circulatory disorders, diabetes, or constant pressure to the skin (decubitus). The hallmarks of modern wound treatment include debridement of dead tissue, disinfection, wound dressings that keep the wound moist but still allow air exchange, and compression bandages. Despite all these efforts there is still a huge treatment resistance and wounds will not heal. This calls for new and more efficient treatment options in combination with novel biocompatible skin scaffolds. Cold atmospheric pressure plasma (CAP) is such an innovative addition to the treatment armamentarium. In one CAP application, antimicrobial effects, wound acidification, enhanced microcirculations and cell stimulation can be achieved. It is evident that CAP treatment, in combination with novel bioengineered, biocompatible and biodegradable electrospun scaffolds, has the potential of fostering wound healing by promoting remodeling and epithelialization along such temporarily applied skin replacement scaffolds. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/22/17/9199; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms22179199 |
| URL الوصول: | https://doaj.org/article/1eb371744e9f4c4d8b6eef16b1358c63 |
| رقم الأكسشن: | edsdoj.1eb371744e9f4c4d8b6eef16b1358c63 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
|---|---|
| DOI: | 10.3390/ijms22179199 |