دورية أكاديمية
Genomic Epidemiology of Global Carbapenemase-Producing Escherichia coli, 2015–2017
| العنوان: | Genomic Epidemiology of Global Carbapenemase-Producing Escherichia coli, 2015–2017 |
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| المؤلفون: | Gisele Peirano, Liang Chen, Diego Nobrega, Thomas J. Finn, Barry N. Kreiswirth, Rebekah DeVinney, Johann D.D. Pitout |
| المصدر: | Emerging Infectious Diseases, Vol 28, Iss 5, Pp 924-931 (2022) |
| بيانات النشر: | Centers for Disease Control and Prevention, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | E. coli, surveillance, carbapenemases, molecular epidemiology, whole-genome sequencing, Escherichia coli, Medicine, Infectious and parasitic diseases, RC109-216 |
| الوصف: | We describe the global molecular epidemiology of 229 carbapenemase-producing Escherichia coli in 36 countries during 2015–2017. Common carbapenemases were oxacillinase (OXA) 181 (23%), New Delhi metallo-β-lactamase (NDM) 5 (20%), OXA-48 (17%), Klebsiella pneumoniae carbapenemase 2 (15%), and NDM-1 (10%). We identified 5 dominant sequence types (STs); 4 were global (ST410, ST131, ST167, and ST405), and 1 (ST1284) was limited to Turkey. OXA-181 was frequent in Jordan (because of the ST410-B4/H24RxC subclade) and Turkey (because of ST1284). We found nearly identical IncX3-blaOXA-181 plasmids among 11 STs from 12 countries. NDM-5 was frequent in Egypt, Thailand (linked with ST410-B4/H24RxC and ST167-B subclades), and Vietnam (because of ST448). OXA-48 was common in Turkey (linked with ST11260). Global K. pneumoniae carbapenemases were linked with ST131 C1/H30 subclade and NDM-1 with various STs. The global carbapenemase E. coli population is dominated by diverse STs with different characteristics and varied geographic distributions, requiring ongoing genomic surveillance. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1080-6040 1080-6059 |
| Relation: | https://wwwnc.cdc.gov/eid/article/28/5/21-2535_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059 |
| DOI: | 10.3201/eid2805.212535 |
| URL الوصول: | https://doaj.org/article/c1eb3df6e1b047f2b5061b42c7ecce75 |
| رقم الأكسشن: | edsdoj.1eb3df6e1b047f2b5061b42c7ecce75 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 10806040 10806059 |
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| DOI: | 10.3201/eid2805.212535 |