دورية أكاديمية
Factors Associated With Precancerous Cervical Lesions in Human Immunodeficiency Virus–Infected Women: A Cross-Sectional Survey in Togo
| العنوان: | Factors Associated With Precancerous Cervical Lesions in Human Immunodeficiency Virus–Infected Women: A Cross-Sectional Survey in Togo |
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| المؤلفون: | Tchin Darré, Toukilnan Djiwa, Karell Josiane Ogniadé Ladekpo, Bingo K M’Bortche, Baguilane Douaguibe, Abdoul-Samadou Aboubakari, Didier Koumavi Ekouévi, Bayaki Saka |
| المصدر: | Clinical Medicine Insights: Oncology, Vol 18 (2024) |
| بيانات النشر: | SAGE Publishing, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Background: The burden of human immunodeficiency virus (HIV) in cervical cancer remains a major public health challenge in developing countries, like Togo. Precancerous lesions include all cellular abnormalities that have malignant potential that can develop into cancer. The objective of this study was to determine the prevalence and factors associated with precancerous cervical lesions in HIV-infected women in our context. Methods: A cross-sectional descriptive study was carried out from November 31, 2022, to January 31, 2023, in an HIV care center in Lomé (Non-Governmental Organization Espoir Vie Togo [NGO EVT] Grand-Lomé-Togo). Results: A total of 271 women were included with a mean age of 47.0 years and a standard deviation of 10.0 years, among whom 20.7% do not have any scholar education. Only 6.7% of them had previously performed cervical smear examinations. The prevalence of precancerous cervical lesions observed in people living with human immunodeficiency virus (PLHIV) was 11.4% with a 95% confidence interval (CI) of 5.0 to 15.4. Cytological abnormalities were marked by low-grade squamous intraepithelial lesion (LSIL) (5.1%), followed by the presence of atypical squamous cells of undetermined significance (ASCUS) (3.5%). A statistically significant association was found between parity and the presence of precancerous lesions ( P = .014). Conclusions: In this study, more than 1 out of 10 women living with HIV had precancerous cervical lesions, and parity was the factor associated. The implementation of a systematic screening program for precancerous cervical lesions and human papillomavirus (HPV) infection integrated into HIV care is necessary for early treatment. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1179-5549 11795549 |
| Relation: | https://doaj.org/toc/1179-5549 |
| DOI: | 10.1177/11795549241234620 |
| URL الوصول: | https://doaj.org/article/1f8674b2234640cf813842bda683be4e |
| رقم الأكسشن: | edsdoj.1f8674b2234640cf813842bda683be4e |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 11795549 |
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| DOI: | 10.1177/11795549241234620 |