دورية أكاديمية
An Assessment of the Effects of Guanidinoacetic Acid on the Performance and Immune Response of Laying Hens Fed Diets with Three Levels of Metabolizable Energy
| العنوان: | An Assessment of the Effects of Guanidinoacetic Acid on the Performance and Immune Response of Laying Hens Fed Diets with Three Levels of Metabolizable Energy |
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| المؤلفون: | Santiago García-Gómora, Gabriela Gómez-Verduzco, Claudia C. Márquez-Mota, Arturo Cortés-Cuevas, Oscar Vicente Vazquez-Mendoza, Ernesto Ávila-González |
| المصدر: | Animals, Vol 14, Iss 11, p 1675 (2024) |
| بيانات النشر: | MDPI AG, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Veterinary medicine LCC:Zoology |
| مصطلحات موضوعية: | guanidinoacetic acid, laying hens, low energy levels, Veterinary medicine, SF600-1100, Zoology, QL1-991 |
| الوصف: | Different levels of metabolizable energy (ME) and the inclusion of guanidinoacetic acid (GAA) in the diet of 53-week-old Lohmann LSL-CLASSIC hens were used to evaluate its effect on reproductive parameters, egg quality, intestinal morphology, and the immune response. Six diets were used in a 3 × 2 factorial design, with three levels of ME (2850, 2800, and 2750 kcal/kg), and with (0.08%) or without the inclusion of GAA. The addition of GAA to diets with low levels of ME increased (p < 0.05) egg production and egg mass. Moreover, hens fed with 2800 kcal/g without GAA had the highest concentration (p < 0.05) of serum interleukin IL-2, while those fed diets with the same amount of ME but supplemented with 0.08% GAA had the lowest concentration. Finally, the inclusion of 0.08% GAA increased (p < 0.05) the concentration of vascular endothelial growth factor (VEGF), regardless of the ME level in the diet. This study highlights the potential role of GAA in decreasing the energy level of ME (50–100 kcal/g) in the feeding of hens and in the modulation of specific immune responses. Further research is recommended to fully understand the mechanisms of action of GAA on the mechanism target of rapamycin and its relationship with the immune response. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 14111675 2076-2615 |
| Relation: | https://www.mdpi.com/2076-2615/14/11/1675; https://doaj.org/toc/2076-2615 |
| DOI: | 10.3390/ani14111675 |
| URL الوصول: | https://doaj.org/article/dac1fa9cae044acbb5a225e92e86750f |
| رقم الأكسشن: | edsdoj.1fa9cae044acbb5a225e92e86750f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14111675 20762615 |
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| DOI: | 10.3390/ani14111675 |