دورية أكاديمية
Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study.
| العنوان: | Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study. |
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| المؤلفون: | Ruth F Dubin, Mary Whooley, Alexander Pico, Peter Ganz, Nelson B Schiller, Craig Meyer |
| المصدر: | PLoS ONE, Vol 13, Iss 12, p e0208042 (2018) |
| بيانات النشر: | Public Library of Science (PLoS), 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | BACKGROUND:Patients with chronic kidney disease (CKD) are at increased risk for heart failure (HF). We aimed to investigate differences in proteins associated with HF hospitalizations among patients with and without CKD in the Heart and Soul Study. METHODS AND RESULTS:We measured 1068 unique plasma proteins from baseline samples of 974 participants in The Heart and Soul Study who were followed for HF hospitalization over a median of 7 years. We sequentially applied forest regression and Cox survival analyses to select prognostic proteins. Among participants with CKD, four proteins were associated with HF at Bonferroni-level significance (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1932-6203 |
| Relation: | https://doaj.org/toc/1932-6203 |
| DOI: | 10.1371/journal.pone.0208042 |
| URL الوصول: | https://doaj.org/article/1fd86528d7e040b097b38299eea62486 |
| رقم الأكسشن: | edsdoj.1fd86528d7e040b097b38299eea62486 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19326203 |
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| DOI: | 10.1371/journal.pone.0208042 |