دورية أكاديمية
Comparison of Prognostic Performance between Procalcitonin and Procalcitonin-to-Albumin Ratio in Post Cardiac Arrest Syndrome
| العنوان: | Comparison of Prognostic Performance between Procalcitonin and Procalcitonin-to-Albumin Ratio in Post Cardiac Arrest Syndrome |
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| المؤلفون: | Ju Hee Yoon, Woo Sung Choi, Yong Su Lim, Jae Ho Jang |
| المصدر: | Journal of Clinical Medicine, Vol 12, Iss 14, p 4568 (2023) |
| بيانات النشر: | MDPI AG, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | post cardiac arrest syndrome, prognosis, procalcitonin to albumin ratio, mortality, neurologic outcome, Medicine |
| الوصف: | (1) Background: Post-cardiac arrest syndrome (PCAS) is a type of global ischemic reperfusion injury that occurs after the return of spontaneous circulation (ROSC). The procalcitonin to albumin ratio (PAR) has been studied as an independent prognostic factor of various diseases. There are no previous studies of PAR in patients with PCAS. We assessed if PAR is more effective than procalcitonin (PCT) in predicting prognosis for patients with PCAS. (2) Methods: This retrospective cohort study included a total of 187 patients with PCAS after non-traumatic out-of-hospital cardiac arrest (OHCA) between January 2016 and December 2020. Multivariate logistic regression analysis was conducted to assess the association between PAR and PCAS prognosis. The predictive performance of PAR was compared with PCT via the receiver-operating characteristic (ROC) analysis and DeLong test.; (3) Results: PAR at 24 and 48 h after hospital admission were independently associated with one-month neurological outcome (OR: 1.167, 95% CI: 1.023–1.330; OR: 1.077, 95% CI: 1.012–1.146, p < 0.05). By ROC analysis, PAR showed better performance over PCT at 48 h after admission in predicting one-month CPC (0.763 vs. 0.772, p = 0.010). (4) Conclusions: Our findings suggest that PAR at 48 h after admission is more effective in predicting a one-month neurological outcome than PCT at 48 h after admission in patients with PCAS after OHCA. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 12144568 2077-0383 |
| Relation: | https://www.mdpi.com/2077-0383/12/14/4568; https://doaj.org/toc/2077-0383 |
| DOI: | 10.3390/jcm12144568 |
| URL الوصول: | https://doaj.org/article/201c4ece363343e1ac6808b3b2a403e6 |
| رقم الأكسشن: | edsdoj.201c4ece363343e1ac6808b3b2a403e6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 12144568 20770383 |
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| DOI: | 10.3390/jcm12144568 |