دورية أكاديمية
Association analysis of polymorphisms of G protein-coupled receptor 54 gene exons with reproductive traits in Jiaxing Black sows
| العنوان: | Association analysis of polymorphisms of G protein-coupled receptor 54 gene exons with reproductive traits in Jiaxing Black sows |
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| المؤلفون: | Fen Wu, Wei Zhang, Qian-Qian Song, Hai-Hong Li, Ming-Shu Xu, Guo-Liang Liu, Jin-Zhi Zhang |
| المصدر: | Asian-Australasian Journal of Animal Sciences, Vol 32, Iss 8, Pp 1104-1111 (2019) |
| بيانات النشر: | Asian-Australasian Association of Animal Production Societies, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Animal culture LCC:Animal biochemistry |
| مصطلحات موضوعية: | Jiaxing Black Sows, G Protein-coupled Receptor 54 (), Single Nucleotide Polymorphisms, Reproductive Traits, Animal culture, SF1-1100, Animal biochemistry, QP501-801 |
| الوصف: | Objective The aim of this study was to detect single nucleotide polymorphisms (SNP) of G protein-coupled receptor 54 (GPR54) gene and explore association of this candidate gene with reproductive traits in Jiaxing Black sows. Methods Six pairs of primers of the gene were designed to amplify all exons thus sequences of which were detected by means of direct sequencing and then SNP loci were scanned. The effects of SNPs on total number of piglets born (TNB), number of piglets born alive (NBA), number of still born piglets (NSB), and litter weight at birth (LWB) of Jiaxing Black sows were analyzed. Results Three SNP loci, including T3739C, C3878T and T6789C, were identified via comparison of sequencing and two genotypes (AB, BB) at each SNP site were observed. T3739C resulted in the change of amino acid (Leu→Pro) in corresponding protein, and C3878T resulted in synonymous mutation (Ile→Ile). Statistical results demonstrated that allele B was the preponderant allele at the three SNP loci and Genotype BB was the preponderant genotype. Meanwhile, Chi-Square test of these three SNPs indicated that all mutation sites fitted in Hardy-Weinberg equilibrium (p>0.05). For GPR54-T3739C locus, Jiaxing Black sows with genotype BB had 1.23 TNB and 1.28 NBA (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1011-2367 1976-5517 |
| Relation: | http://www.ajas.info/upload/pdf/ajas-18-0827.pdf; https://doaj.org/toc/1011-2367; https://doaj.org/toc/1976-5517 |
| DOI: | 10.5713/ajas.18.0827 |
| URL الوصول: | https://doaj.org/article/e205820796fe45b8bde4d8c442fedb17 |
| رقم الأكسشن: | edsdoj.205820796fe45b8bde4d8c442fedb17 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 10112367 19765517 |
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| DOI: | 10.5713/ajas.18.0827 |