دورية أكاديمية
Radiopharmaceuticals for Skeletal Muscle PET Imaging
| العنوان: | Radiopharmaceuticals for Skeletal Muscle PET Imaging |
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| المؤلفون: | Joo Yeon Park, Sun Mi Park, Tae Sup Lee, Seo Young Kang, Ji-Young Kim, Hai-Jeon Yoon, Bom Sahn Kim, Byung Seok Moon |
| المصدر: | International Journal of Molecular Sciences, Vol 25, Iss 9, p 4860 (2024) |
| بيانات النشر: | MDPI AG, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | positron emission tomography, radiopharmaceutical, skeletal muscle atrophy, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | The skeletal muscles account for approximately 40% of the body weight and are crucial in movement, nutrient absorption, and energy metabolism. Muscle loss and decline in function cause a decrease in the quality of life of patients and the elderly, leading to complications that require early diagnosis. Positron emission tomography/computed tomography (PET/CT) offers non-invasive, high-resolution visualization of tissues. It has emerged as a promising alternative to invasive diagnostic methods and is attracting attention as a tool for assessing muscle function and imaging muscle diseases. Effective imaging of muscle function and pathology relies on appropriate radiopharmaceuticals that target key aspects of muscle metabolism, such as glucose uptake, adenosine triphosphate (ATP) production, and the oxidation of fat and carbohydrates. In this review, we describe how [18F]fluoro-2-deoxy-D-glucose ([18F]FDG), [18F]fluorocholine ([18F]FCH), [11C]acetate, and [15O]water ([15O]H2O) are suitable radiopharmaceuticals for diagnostic imaging of skeletal muscles. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/25/9/4860; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms25094860 |
| URL الوصول: | https://doaj.org/article/aa213fcf81b7445e8b695398db84739a |
| رقم الأكسشن: | edsdoj.213fcf81b7445e8b695398db84739a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
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| DOI: | 10.3390/ijms25094860 |