دورية أكاديمية
The Drug Metabolism and Pharmacokinetics Investigation about Baicalin Effect and Baicalein on Mice U14 Cervical Cancer
العنوان: | The Drug Metabolism and Pharmacokinetics Investigation about Baicalin Effect and Baicalein on Mice U14 Cervical Cancer |
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المؤلفون: | Zhanzhao Fu, Ya Di, Liming Gao, Jiandong Wu, Ming Shi, Fulu Zheng |
المصدر: | Journal of Spectroscopy, Vol 2015 (2015) |
بيانات النشر: | Hindawi Limited, 2015. |
سنة النشر: | 2015 |
المجموعة: | LCC:Optics. Light |
مصطلحات موضوعية: | Optics. Light, QC350-467 |
الوصف: | The experiment studies the effect of baicalin and baicalein on mice U14 cervical cancer and its pharmacokinetics in mice. By using different mouse models of cancer treatment program administered and uptake kinetics experiments, tissue distribution experiment, excretion, and metabolism in experimental experiments, we found that baicalin and baicalein can improve immunity and the ability of antioxidation and inhibit the growth of tumor. The absorption of intestinal drug takes place in intestinal tract. Tissue distribution was ideal. Because of the ideal drug distribution, the liver and kidney were protected. Drug was mainly excreted through the feces and bile excretion. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2314-4920 2314-4939 21860521 |
Relation: | https://doaj.org/toc/2314-4920; https://doaj.org/toc/2314-4939 |
DOI: | 10.1155/2015/632062 |
URL الوصول: | https://doaj.org/article/21860521016a4d5aa12854c8a1272c92 |
رقم الأكسشن: | edsdoj.21860521016a4d5aa12854c8a1272c92 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 23144920 23144939 21860521 |
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DOI: | 10.1155/2015/632062 |