دورية أكاديمية
Clinical Features of Chronic Obstructive Pulmonary Disease with High Fractional Exhaled Nitric Oxide
| العنوان: | Clinical Features of Chronic Obstructive Pulmonary Disease with High Fractional Exhaled Nitric Oxide |
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| المؤلفون: | Seong Ahn, Tae-Ok Kim, Jinsun Chang, Hong-Joon Shin, Yong-Soo Kwon, Sung-Chul Lim, Yu-Il Kim |
| المصدر: | Tuberculosis and Respiratory Diseases, Vol 83, Iss 3, Pp 234-241 (2020) |
| بيانات النشر: | The Korean Academy of Tuberculosis and Respiratory Diseases, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Diseases of the respiratory system |
| مصطلحات موضوعية: | nitric oxide, pulmonary disease, chronic obstructive, asthma-chronic obstructive pulmonary disease overlap syndrome, Diseases of the respiratory system, RC705-779 |
| الوصف: | Background The fractional exhaled nitric oxide (FENO) test is useful in asthma patients. However, a few studies on its usefulness in chronic obstructive pulmonary disease (COPD) patients have been reported. We analyzed the FENO level distribution and clinical characteristics according to the FENO level in COPD patients. Methods From December 2014 to June 2019, COPD patients who underwent pulmonary function and FENO tests at Chonnam National University Hospital were retrospectively evaluated for FENO, comorbidities, asthma history, blood eosinophil, and pulmonary function test. The high FENO group was defined as those with FENO level>25 parts per billion (ppb). Results A total of 849 COPD patients (mean age, 70.3±9.4 years) were included. The mean forced expiratory volume at 1 second was 66.5±21.7% and the mean FENO level was 24.3±20.5 ppb. Patients with FENO ≤25 ppb were 572 (67.4%) and those with FENO >25 ppb were 277 (32.6%). Blood eosinophil percentage was significantly higher (4.2±4.8 vs. 2.7±2.5, p3% (46.9% vs. 34.8%, p=0.001) and asthma history (25.6% vs. 8.6%, p3%, and positive bronchodilator response (BDR) were independent risk factors for the high FENO level (adjusted odds ratio [aOR], 3.85; p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1738-3536 2005-6184 |
| Relation: | http://www.e-trd.org/upload/pdf/trd-2019-0086.pdf; https://doaj.org/toc/1738-3536; https://doaj.org/toc/2005-6184 |
| DOI: | 10.4046/trd.2019.0086 |
| URL الوصول: | https://doaj.org/article/21bda3c2c4ce49688611ecb7701f9ba1 |
| رقم الأكسشن: | edsdoj.21bda3c2c4ce49688611ecb7701f9ba1 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17383536 20056184 |
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| DOI: | 10.4046/trd.2019.0086 |