دورية أكاديمية
Influence of diabetes mellitus on the biochemical parameters and outcomes of multiple myeloma
| العنوان: | Influence of diabetes mellitus on the biochemical parameters and outcomes of multiple myeloma |
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| المؤلفون: | Zheng-Yue Dou, Bing Xia, Chao-Yu Wang, Yan-Jie Xu, Yi-Zhuo Zhang |
| المصدر: | Hematology, Vol 28, Iss 1 (2023) |
| بيانات النشر: | Taylor & Francis Group, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Diseases of the blood and blood-forming organs |
| مصطلحات موضوعية: | Type 2 diabetes mellitus, multiple myeloma, diagnosis and treatment, influence, biochemical parameters, steroids, Diseases of the blood and blood-forming organs, RC633-647.5 |
| الوصف: | ABSTRACTObjective: The incidence of MM in most registries remains stable or showing only a slightly increase. However, prevalence of MM is increasing due to the increase in overall survival in the last two decades. The aim of this study was to observe changes in biochemical parameters during the diagnosis and treatment of MM.Methods: A retrospective analysis was made of the biochemical indicators, survival time, and related adverse events of 196 patients with MM.Results: Of the 196 patients with MM, 26 were diagnosed with DM (DM-MM group) at the first diagnosis, 31 with steroid-induced diabetes mellitus (SID-MM group) during treatment, and 139 without DM (MM group). There was no significant difference between the three groups in the mean age of onset, sex ratio, incidence of hypercalcemia, renal dysfunction, anemia, abnormal lactate dehydrogenase, and median value of D-dimer and fibrinogen during diagnosis and treatment. There was no significant difference in survival time between the SID-MM and MM groups, but there was a significant difference between the DM-MM and MM groups.Conclusion: There was no significant difference between the three groups in the incidence of hypercalcemia, anemia, and renal function impairment. The survival time of patients with DM was shorter than that of patients without DM. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 16078454 1607-8454 |
| Relation: | https://doaj.org/toc/1607-8454 |
| DOI: | 10.1080/16078454.2023.2179218 |
| URL الوصول: | https://doaj.org/article/21da9ff47bf74dfc85634005427527f4 |
| رقم الأكسشن: | edsdoj.21da9ff47bf74dfc85634005427527f4 |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 16078454 |
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| DOI: | 10.1080/16078454.2023.2179218 |