دورية أكاديمية
Adiaspiromicose humana. Relato de um caso tratado com cetoconazol
| العنوان: | Adiaspiromicose humana. Relato de um caso tratado com cetoconazol |
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| المؤلفون: | Ricardo Luiz M. Martins, Clarice G. F. Santos, Filomena Rita F.C. França, Mário A.P. Moraes |
| المصدر: | Revista da Sociedade Brasileira de Medicina Tropical, Vol 30, Iss 6, Pp 507-509 (1997) |
| بيانات النشر: | Sociedade Brasileira de Medicina Tropical (SBMT), 1997. |
| سنة النشر: | 1997 |
| المجموعة: | LCC:Arctic medicine. Tropical medicine |
| مصطلحات موضوعية: | Adiaspiromicose, Chrysosporium parvum var crescens, Emmonsia crescens, Micose pulmonar, Adiaspiromycosis, Pulmonary mycosis, Arctic medicine. Tropical medicine, RC955-962 |
| الوصف: | É descrito um caso de adiaspiromicose humana, da forma pulmonar disseminada, no qual se empregou o cetoconazol. O paciente, oriundo de Goianésia, GO, referia tosse produtiva, dispnéia e emagrecimento. Doente há dois meses, já fizera uso do esquema tríplice tuberculostático, devido a um radiograma do tórax ter acusado lesões sugestivas de tuberculose miliar. Esse tratamento não surtiu o efeito esperado, pelo que foi ele submetido a uma biópsia pulmonar a céu aberto. A medida permitiu o reconhecimento da natureza fúngica da doença. Passou-se, então, ao emprego do cetoconazol, quando o processo já completara três meses de evolução. Dois meses depois, foi o paciente novamente visto, para controle do tratamento: todas as manifestações respiratórias haviam cessado e um novo radiograma mostrou regressão completa das alterações pulmonares. Apesar disso, é discutida a eficácia do cetoconazol contra C. parvum var crescens, tendo-se em conta o fato de o microrganismo não se reproduzir no hospedeiro.A case of human disseminated pulmonary adiaspiromycosis is reported. The patient, from Goianesia, GO, was admitted to the Brasilia University Hospital, in November 1992, with wet cough, dyspnea and weight loss3/4manifestations that had appeared two months before. Prior to admission, he had been treated for a suspected miliary tuberculosis, because a chest roentgenogram had shown a diffuse reticulonodular infiltrate in both lungs. This therapy brought no improvement to the patient status. An open chest biopsy was then performed, and the microscopic examination of the lung tissue revealed the fungal nature of the disease. Ketoconazole, 400mg/day, was started and the patient discharged from the hospital. He was seen again two months later: the respiratory manifestations had disappeared and a new chest roentgenogram showed complete resolution of the pulmonary lesions. The usefulness of ketoconazole is, however, questioned, since, as there is no multiplication of the fungus in the host organism3/4adiaspiromycosis. is believed to be, usually, a self-healing disease -, the efficacy of this imidazole derivative against the agent in animal tissues remains to be confirmed. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0037-8682 1678-9849 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821997000600011; https://doaj.org/toc/0037-8682; https://doaj.org/toc/1678-9849 |
| DOI: | 10.1590/S0037-86821997000600011 |
| URL الوصول: | https://doaj.org/article/21e610153b614c0896ea4c087fd18591 |
| رقم الأكسشن: | edsdoj.21e610153b614c0896ea4c087fd18591 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 00378682 16789849 |
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| DOI: | 10.1590/S0037-86821997000600011 |