دورية أكاديمية
The First Hospital-Based Registry of Patients with Multiple Sclerosis in Croatia
| العنوان: | The First Hospital-Based Registry of Patients with Multiple Sclerosis in Croatia |
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| المؤلفون: | Vanja Bašić Kes, Marijana Lisak, Miljenka , Jurašić, Iris Zavoreo, Ana Dimitrović, Ivana Kobasić, Lucija Zadro Matovina |
| المصدر: | Acta Clinica Croatica, Vol 56., Iss 3., Pp 487-493 (2017) |
| بيانات النشر: | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | Multiple sclerosis, Registries, Medical records, Disease progression, Croatia, Medicine |
| الوصف: | Th e fi rst hospital-based registry of patients with multiple sclerosis (MS) was established at the University Department of Neurology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia, in 2014. Th e aim of the registry was to continuously provide data on the number of hospital-managed MS patients, patterns of disease progression, predictors of disability progression, changes in lifespan and long-term outcomes. Relevant medical data included age and gender of MS patients, family history of MS, data on previous immunization, disease course, Expanded Disability Status Scale (EDSS) score, cerebral magnetic resonance imaging (MRI) lesion load quantification, and cerebrospinal fl uid analysis. Lifestyle habits in MS patients including smoking and alcohol consumption were also analyzed. All data were obtained from primary medical records between January 1, 2014 and January 1, 2015, and entered into the database. Data were evaluated retrospectively according to age and gender diff erences. Results showed that the majority of patients enrolled in the registry had the remitting relapsing course of disease, with low EDSS score indicating no disability or minimal disability. Cerebrospinal fl uid analysis showed that oligoclonal bands were present in the majority of MS patients, with aff ected blood-brain-barrier permeability. According to the remitting relapsing course of the disease, cerebral MRI quantitative analysis demonstrated a signifi cant lesion load in the majority of patients. When stratifi ed by lifestyle habits, smokers and alcohol consumers were more prevalent among male patients. Our hospital-based registry might be considered as a prototype for the national MS registry and should be improved for reliable statistical analysis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0353-9466 1333-9451 |
| Relation: | https://hrcak.srce.hr/file/282623; https://doaj.org/toc/0353-9466; https://doaj.org/toc/1333-9451 |
| DOI: | 10.20471/acc.2017.56.03.16 |
| URL الوصول: | https://doaj.org/article/d21f945c45a2484bb573ab1c0f86c0f6 |
| رقم الأكسشن: | edsdoj.21f945c45a2484bb573ab1c0f86c0f6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03539466 13339451 |
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| DOI: | 10.20471/acc.2017.56.03.16 |