دورية أكاديمية
Serum concentrations of complement C3 and C4 in dogs with idiopathic epilepsy
| العنوان: | Serum concentrations of complement C3 and C4 in dogs with idiopathic epilepsy |
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| المؤلفون: | Seonggweon Kang, Yoonhoi Koo, Taesik Yun, Yeon Chae, Dohee Lee, Hakhyun Kim, Mhan‐Pyo Yang, Byeong‐Teck Kang |
| المصدر: | Journal of Veterinary Internal Medicine, Vol 38, Iss 2, Pp 1074-1082 (2024) |
| بيانات النشر: | Wiley, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Veterinary medicine |
| مصطلحات موضوعية: | biomarker, classical pathway, neuroinflammation, seizure, Veterinary medicine, SF600-1100 |
| الوصف: | Abstract Background High concentrations of complement factors are presented in serum of animal epilepsy models and human patients with epilepsy. Objectives To determine whether complement dysregulation occurs in dogs with idiopathic epilepsy (IE). Animals The study included 49 dogs with IE subgrouped into treatment (n = 19), and nontreatment (n = 30), and 29 healthy dogs. Methods In this case‐control study, the serum concentrations of the third (C3) and fourth (C4) components of the complement system were measured using a canine‐specific ELISA kit. Results Serum C3 and C4 concentrations were significantly higher in dogs with IE (C3, median; 4.901 [IQR; 3.915‐6.673] mg/mL, P 3 times/month had significantly higher serum C3 (6.461 [4.695‐8.735] mg/mL; P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1939-1676 0891-6640 |
| Relation: | https://doaj.org/toc/0891-6640; https://doaj.org/toc/1939-1676 |
| DOI: | 10.1111/jvim.17008 |
| URL الوصول: | https://doaj.org/article/22a0588c78904808943bd49f528e2cc0 |
| رقم الأكسشن: | edsdoj.22a0588c78904808943bd49f528e2cc0 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19391676 08916640 |
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| DOI: | 10.1111/jvim.17008 |