This paper proposes a sensor-less robust force control method for improving the control performance of an electro-mechanical brake (EMB) which is applicable to commercial city buses. The EMB generates the accurate clamping force commanded by a driver through an independent motor control at each wheel instead of using existing mechanical components. In general, an EMB undergoes parameter variation and a backdrivability problem. For this reason, the cascade control strategy (e.g., force-position cascade control structure) is proposed and the disturbance observer is employed to enhance control robustness against model variations. Additionally, this paper proposed the clamping force estimation method for a sensor-less control, i.e., the clamping force observer (CFO). Finally, in order to confirm the performance and effectiveness of a proposed robust control method, several experiments are performed and analyzed.