دورية أكاديمية
Role of Dietary Macronutrient Composition and Fibre Intake in Development of Double Diabetes in Indian Youth
| العنوان: | Role of Dietary Macronutrient Composition and Fibre Intake in Development of Double Diabetes in Indian Youth |
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| المؤلفون: | Chirantap Oza, Rubina Mandlik, Anuradha V. Khadilkar, Ketan M. Gondhalekar, Vaman V. Khadilkar |
| المصدر: | Indian Journal of Endocrinology and Metabolism, Vol 28, Iss 2, Pp 213-219 (2024) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | double diabetes, fibre, glycaemic control, insulin resistance, macronutrients, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Introduction: Insulin resistance (IR) and obesity are common presentations of double diabetes (DD) in subjects with type-1 diabetes (T1D). There is evidence that dietary composition has an impact on developing IR. Objectives were to assess the impact of macronutrient and fibre intake on glycaemic control and the role of macronutrient composition of diet in the development of DD in subjects with T1D. Methods: This cross-sectional study included 77 young adults (10–25 years) with T1D. Data related to demography, anthropometry, biochemistry and body composition were collected. Dietary data was collected by fourteen-day food diary. IR was calculated using eGDR, SEARCH and CACTI equations, and metabolic syndrome (MS) was diagnosed using the International Diabetes Federation Consensus Definition. Results: Subjects at risk of DD had higher age, leptin levels, percentage carbohydrate consumption in diet and IR. A positive association of insulin sensitivity with fibre intake and %protein intake was noted. Poor glycaemic control, adiponectin/leptin ratio, fibre intake and insulin/carbohydrate ratio were significant negative predictors of IR. Addition of dietary factors to the regression model improved the R square and percentage of subjects identified correctly. Inclusion of dietary parameters significantly improves the prediction of the risk of development of DD in subjects with T1D. Conclusion: Good glycaemic control and increased intake of dietary fibre may prevent the development of IR in subjects with T1D and reduce the burden of DD. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2230-8210 2230-9500 |
| Relation: | https://journals.lww.com/10.4103/ijem.ijem_90_23; https://doaj.org/toc/2230-8210; https://doaj.org/toc/2230-9500 |
| DOI: | 10.4103/ijem.ijem_90_23 |
| URL الوصول: | https://doaj.org/article/2399edbf2d2341f98cedb7a23bb12c22 |
| رقم الأكسشن: | edsdoj.2399edbf2d2341f98cedb7a23bb12c22 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22308210 22309500 |
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| DOI: | 10.4103/ijem.ijem_90_23 |