دورية أكاديمية
Which incision is better for Lewis to Brown Norway rat liver transplantation, transverse or midline?
| العنوان: | Which incision is better for Lewis to Brown Norway rat liver transplantation, transverse or midline? |
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| المؤلفون: | Gaofeng Tang, Huibo Zhao, Guoyong Chen, Shaotang Zhou |
| المصدر: | Heliyon, Vol 9, Iss 7, Pp e18213- (2023) |
| بيانات النشر: | Elsevier, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Science (General) LCC:Social sciences (General) |
| مصطلحات موضوعية: | Orthotopic liver transplantation, Rat, Self-biting, Science (General), Q1-390, Social sciences (General), H1-99 |
| الوصف: | Orthotopic rat liver transplantation (OLT) is a complex microsurgical procedure extensively applied to basic science, myriad complications can occur, but incision-related self-biting has not been reported after OLT. For the project of tolerance induction through stem cells, we performed OLT from Lewis to Brown Norway (BN) rats as an acute rejection model and divided the study was into the transverse incision group (n = 15) and midline incision group (n = 22), while cyclosporine A was subcutaneously injected for 10-day immunosuppression use, lidocaine cream was used for pain-relieving. The recipient survival and wound status were the primary endpoint of this study. For the transverse incision group, 30-day survival rate was 40% (6/15), self-biting occurred in 13 cases in 7–39 days, the degree 1 of biting occurred in 1 cases, the degree 2 in 2 cases. The degree 3 in 10 cases, which caused death or euthanasia, the self-biting rate was 86.7% (13/15), For the midline incision group, 30-day survival rate was 100% (22/22), the degree 1 of self-biting occurred in 3 cases, no severe self-biting occurred. There were significant differences for survival (p = 0.0003) and for self-biting rate (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2405-8440 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S240584402305421X; https://doaj.org/toc/2405-8440 |
| DOI: | 10.1016/j.heliyon.2023.e18213 |
| URL الوصول: | https://doaj.org/article/d23a052e0c5047138c6cacab87878e67 |
| رقم الأكسشن: | edsdoj.23a052e0c5047138c6cacab87878e67 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 24058440 |
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| DOI: | 10.1016/j.heliyon.2023.e18213 |