دورية أكاديمية
Adverse Reaction Following Intravenous Immunoglobulin in Primary Immunodeficiency Patients
| العنوان: | Adverse Reaction Following Intravenous Immunoglobulin in Primary Immunodeficiency Patients |
|---|---|
| المؤلفون: | J. Ghaffari, M.D., M. Gharegozlou, M.D, I. Mohammadzadeh, M.D., Z. Nazari, M.D |
| المصدر: | Journal of Mazandaran University of Medical Sciences, Vol 17, Iss 61, Pp 114-121 (2007) |
| بيانات النشر: | Mazandaran University of Medical Sciences, 2007. |
| سنة النشر: | 2007 |
| المجموعة: | LCC:Medicine LCC:Medicine (General) |
| مصطلحات موضوعية: | Intravenous immunoglobulin, Primary immunodeficiency, Side effects, Medicine, Medicine (General), R5-920 |
| الوصف: | AbstractBackground and Purpose: Intravenous immunoglobulin is used for primary immunodeficiency disorders. There have been some reports that intravenous immunoglobulin causes side effects. The aim of this study was to investigate intravenous immunoglobulin side effects in immunodeficiency patients.Materials and Methods: The study utilized the data of 29 primary immunodeficiency patients that were referred to allergy and immunology department in Medical Children Center in Tehran. 29 patients having completed record data files in the hospital, were the subjects of this study.Results: Of 29 immune deficiency patients (aged 15 months to 55 years), they were 19 Males (65/51%) and 10(34/48%) Females. Prevalence of disorders include common variable immunodeficiency 16(55/17%), Bruton disease 8(27/58%), hyper IgM 4 (13/79%) and severe combind immunodeficiency 1 (3/44%). Based on the recorded data, the duration of infusion has been 5 months to 15 years. 15 patients had reported side effects (51/72%). 34 infusions from the total of 1,626 infusions accompanied with side effects (2/09%). Most side effects were occurred during 30 minutes onset of infusion and most were caused by rapid infusion. Most side effects were mild reactions (fever, chills and …).Conclusion: Intravenous immunoglobulin is a rather safe drug with mild side effects. With an appropriate technique and proper infusion, these side effects can be reduced. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Persian |
| تدمد: | 1735-9260 1735-9279 |
| Relation: | http://www.mazums.ac.ir/index.php?digital_library&do=downloadPdf&sid=555; https://doaj.org/toc/1735-9260; https://doaj.org/toc/1735-9279 |
| URL الوصول: | https://doaj.org/article/23ac4034fdab434190027572b337b025 |
| رقم الأكسشن: | edsdoj.23ac4034fdab434190027572b337b025 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17359260 17359279 |
|---|