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Reasons for Failure of Antifungal-lock Therapy with Caspofungin: Need for Higher Concentrations

التفاصيل البيبلوغرافية
العنوان: Reasons for Failure of Antifungal-lock Therapy with Caspofungin: Need for Higher Concentrations
المؤلفون: Rana İşgüder, Gökhan Ceylan, Özlem Sandal, Ferhat Sarı, Gamze Gülfidan, Bengü Demirağ, Hasan Ağın, İlker Devrim
المصدر: Journal of Pediatric Emergency and Intensive Care Medicine, Vol 4, Iss 1, Pp 30-32 (2017)
بيانات النشر: Galenos Yayinevi, 2017.
سنة النشر: 2017
المجموعة: LCC:Medicine
LCC:Pediatrics
LCC:Medical emergencies. Critical care. Intensive care. First aid
مصطلحات موضوعية: Antifungal kilit tekniği, Candida türleri, kaspofungin, kateter, Medicine, Pediatrics, RJ1-570, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
الوصف: Antifungal-lock therapy (AfLT) has arrived as an investigational approach for preventing catheter removal with limited clinical evidence of its efficiency. The principle of AfLT consists of catheter lumen replenishment by a selected antimicrobial agent and then locking it for an alternative treatment to eradicate the microbes embedded in endoluminal biofilms. Herein, we report a pediatric hematology-oncology patient with Candida parapsilosis-related central venous access device infection in which catheter removal was performed despite the systemic and intraluminal caspofungin treatment. For now, we recommend higher doses of caspofungin for AfLT especially in Candida parapsilosis-related catheter infections.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
Turkish
تدمد: 2146-2399
2148-7332
Relation: http://www.caybdergi.com/article_14841/Reasons-For-Failure-Of-Antifungal-lock-Therapy-With-Caspofungin-Need-For-Higher-Concentrations; https://doaj.org/toc/2146-2399; https://doaj.org/toc/2148-7332
DOI: 10.4274/cayd.83792
URL الوصول: https://doaj.org/article/23b2d39a1b9f415baa6fa08cee47d638
رقم الأكسشن: edsdoj.23b2d39a1b9f415baa6fa08cee47d638
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:21462399
21487332
DOI:10.4274/cayd.83792