دورية أكاديمية
Could Lycopene Protect Against Ischemia/Reperfusion Injury in the Uterus?
| العنوان: | Could Lycopene Protect Against Ischemia/Reperfusion Injury in the Uterus? |
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| المؤلفون: | Taylan Onat, Züleyha Doğanyiğit, Melike Demir Çaltekin, Can Türkler, Emin Kaymak, Mehmet Murat Altındağ |
| المصدر: | İstanbul Medical Journal, Vol 22, Iss 2, Pp 155-160 (2021) |
| بيانات النشر: | Galenos Yayinevi, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | ischemia/reperfusion damage, oxidative stress, organ transplantation, lycopene, Medicine |
| الوصف: | Introduction:Ischemia/reperfusion damage (IRD) is one of the most important factors in the success of organ transplantation. IRD plays a role in both acute and chronic rejection. This study aims to evaluate the effects of lycopene, which is known to be a powerful antioxidant, on experimental uterine IRD.Methods:Twenty-four albino Wistar rats were included in the study and divided into three groups. No substances were administered the sham and ischemia/reperfusion groups. The ischemia/reperfusion and ischemia/reperfusion + lycopene groups were administered ischemia for 1 h and reperfusion for 2 h. The ischemia/reperfusion + lycopene group was administered 2.5 mg/kg lycopene reperfusion intraperitoneally half an hour before ischemia/reperfusion. Both uterine horns were extracted at the end of the procedure. Oxidative stress, inflammation, and apoptosis in the tissues were assessed.Results:The malondialdehyde level, nuclear factor kappa-B immunoreactivity, and apoptotic cell number in the lycopeneadministered group (ischemia/reperfusion + lycopene) were significantly decreased compared with those in the ischemia/ reperfusion group (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2619-9793 2148-094X |
| Relation: | http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/could-lycopene-protect-against-schemia-reperfusion/47291; https://doaj.org/toc/2619-9793; https://doaj.org/toc/2148-094X |
| DOI: | 10.4274/imj.galenos.2021.82698 |
| URL الوصول: | https://doaj.org/article/2403617ac1984b7280db7cb6ee3e466c |
| رقم الأكسشن: | edsdoj.2403617ac1984b7280db7cb6ee3e466c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 26199793 2148094X |
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| DOI: | 10.4274/imj.galenos.2021.82698 |