دورية أكاديمية
Bone marrow aspirate concentrate/platelet-rich fibrin augmentation accelerates healing of aseptic upper limb nonunions
| العنوان: | Bone marrow aspirate concentrate/platelet-rich fibrin augmentation accelerates healing of aseptic upper limb nonunions |
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| المؤلفون: | Alessandro Mazzotta, Cesare Stagni, Martina Rocchi, Nicola Rani, Nicolandrea Del Piccolo, Giuseppe Filardo, Dante Dallari |
| المصدر: | Journal of Orthopaedics and Traumatology, Vol 22, Iss 1, Pp 1-9 (2021) |
| بيانات النشر: | SpringerOpen, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Orthopedic surgery |
| مصطلحات موضوعية: | Orthopedic surgery, RD701-811 |
| الوصف: | Abstract Introduction Nonunions remain a significant burden in orthopedics, often afflicting young males of working age. Positive findings have been published using bone marrow aspirate concentrate (BMAC) and platelet-rich fibrin (PRF) for the treatment augmentation of lower limb nonunions. The aim of this study was to investigate if the treatment augmentation with BMAC and PRF can also accelerate the healing of nonunions of the upper limb. Materials and methods Sixty-eight patients (45 men, 23 women) affected by 75 nonunions of long bones of the upper limb were treated and divided into two groups. The first series was treated with standard surgery alone (group A); afterwards, the second series benefited from standard surgery with the addition of BMAC and PRF applied on lyophilized bone chips. Nonunions were classified radiographically according to the Weber–Cech method and prognostically using the Calori and Moghaddam scores. All patients were radiographically assessed at 1.5, 3, 6, 12, and 24 months of follow-up. Results Baseline demographic characteristics did not present differences between groups. No differences were documented in terms of complications (two in group A and three in group B). Significant differences were instead documented in terms of healing time. The first healing signs were observed 1.5 months after surgery in 90.7% of patients in group B and 34.4% of group A (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1590-9921 1590-9999 |
| Relation: | https://doaj.org/toc/1590-9921; https://doaj.org/toc/1590-9999 |
| DOI: | 10.1186/s10195-021-00582-y |
| URL الوصول: | https://doaj.org/article/247f39a310cc41faa5e53453f5afa9d1 |
| رقم الأكسشن: | edsdoj.247f39a310cc41faa5e53453f5afa9d1 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 15909921 15909999 |
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| DOI: | 10.1186/s10195-021-00582-y |