دورية أكاديمية
Relationship between the prevalence of hemoglobin S and the ethnic background of blood donors in Paraná state
| العنوان: | Relationship between the prevalence of hemoglobin S and the ethnic background of blood donors in Paraná state |
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| المؤلفون: | Kárita C. F. Lidani, Rodrigo F. Barros, Fernanda Bovo |
| المصدر: | Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 51, Iss 4, Pp 212-217 (2015) |
| بيانات النشر: | Sociedade Brasileira de Patologia Clínica, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Pathology |
| مصطلحات موضوعية: | hemoglobina S, doadores de sangue, prevalência, Pathology, RB1-214 |
| الوصف: | ABSTRACTIntroduction:Hemoglobin S (HbS) is one of the most common inherited hematological disorders in humans. In Brazil, the sickle-cell disease (SCD) has significant epidemiological importance due to its prevalence and the morbidity-mortality and, therefore, it has been identified as a matter of public health.Objective:To determine the prevalence of HbS among Asian Brazilian, Afro Brazilian, and Euro Brazilian individuals of a blood bank in Curitiba.Material and method:The study was conducted from January 2008 to December 2009, and included 83,213 donors seen at the Instituto Paranaense de Hemoterapia e Hematologia.Results and discussion:The prevalence of HbS in the studied population was 0.9%, among them, 0% Asian Brazilians, 2.7% Afro Brazilians, and 0.7% Euro Brazilians. There was a positive association, statistically significant for the sickle cell trait in Afro-descendants, with odds ratio (OR) 4.01; confidence interval (CI) 3.42-4.72; and 95% confidence.Conclusion:This study showed higher rates of sickle cell trait in Afro Brazilians, which corroborates data published in other Brazilian regions and states. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-4774 1676-2444 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442015000400212&lng=en&tlng=en; https://doaj.org/toc/1678-4774 |
| DOI: | 10.5935/1676-2444.20150035 |
| URL الوصول: | https://doaj.org/article/24b0b3d1a25e453caa81e196074d1cae |
| رقم الأكسشن: | edsdoj.24b0b3d1a25e453caa81e196074d1cae |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16784774 16762444 |
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| DOI: | 10.5935/1676-2444.20150035 |