دورية أكاديمية
Oxidative Status and Thiol/Disulfide Homeostasis Are Changed During 75 g Oral Glucose Tolerance Test over a Five-Hour Period
| العنوان: | Oxidative Status and Thiol/Disulfide Homeostasis Are Changed During 75 g Oral Glucose Tolerance Test over a Five-Hour Period |
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| المؤلفون: | Zeynep Küskü Kiraz, Ezgi Kar, Fatih Kar, Evin Kocatürk, Medine Nur Kebapçı, İ. Özkan Alataş, Sema Uslu |
| المصدر: | Journal of Investigative Surgery, Vol 35, Iss 8, Pp 1626-1634 (2022) |
| بيانات النشر: | Taylor & Francis Group, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Surgery |
| مصطلحات موضوعية: | oral], glucose tolerance test, oxidative stress, total antioxidant status, total oxidant status, thiol-disulfide, Surgery, RD1-811 |
| الوصف: | Background Oral glucose loading may affect oxidative status during oral glucose tolerance test (OGTT). We aimed to investigate how oxidant and antioxidant markers and thiol/disulfide parameters change during OGTT. Methods OGTT was performed to 42 volunteers who were considered risk of type 2 diabetes and were divided into three groups (normoglycemic, prediabetes, diabetes) according glucose levels during OGTT. Glucose, insulin, c-peptide, total antioxidant status (TAS), total oxidant status (TOS), total thiol and native thiol were investigated with auto-anaylzer for five-hours period. Results Decrease of TAS and increase of TOS levels began with the increase in glucose and insulin levels. The increase of TAS started at third hour and reached the highest levels at fifth hour. OSI levels were higher at fourth hour than fasting and first hours in normoglycemic and diabetes groups. In the prediabetic group, TAS were higher than the other groups, TOS peak was at the second hour (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0894-1939 1521-0553 08941939 |
| Relation: | https://doaj.org/toc/0894-1939; https://doaj.org/toc/1521-0553 |
| DOI: | 10.1080/08941939.2022.2084189 |
| URL الوصول: | https://doaj.org/article/24e3b2136334442a8a1c385d4437d3fe |
| رقم الأكسشن: | edsdoj.24e3b2136334442a8a1c385d4437d3fe |
| قاعدة البيانات: | Directory of Open Access Journals |
PDF full text from Publisher | تدمد: | 08941939 15210553 |
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| DOI: | 10.1080/08941939.2022.2084189 |