Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida

التفاصيل البيبلوغرافية
العنوان:	Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida
المؤلفون:	Shu Shun Li, Henry Ogbomo, Michael K. Mansour, Richard F. Xiang, Lian Szabo, Fay Munro, Priyanka Mukherjee, Roy A. Mariuzza, Matthias Amrein, Jatin M. Vyas, Stephen M. Robbins, Christopher H. Mody
المصدر:	Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
بيانات النشر:	Nature Portfolio, 2018.
سنة النشر:	2018
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Natural killer (NK) cells has been show to mediate fungi killing via the activating receptor NKp30, but the fungal target for NKp30 is still unclear. Here the authors show, using atomic force microscopy and live cell imaging, that β-1,3-glucan is expressed by Cryptococcus neoformans and Candida albicans and responsible for NKp30-mediated NK killing.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-018-03014-4
URL الوصول:	https://doaj.org/article/2544882c0af34f56b6d9c66dfded2082
رقم الأكسشن:	edsdoj.2544882c0af34f56b6d9c66dfded2082
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-018-03014-4