دورية أكاديمية
The Most Important Metabolic Risk Factors in Recurrent Urinary Stone Formers
العنوان: | The Most Important Metabolic Risk Factors in Recurrent Urinary Stone Formers |
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المؤلفون: | Mohaddeseh Azadvari, Sanaz Eftekhari, Peyman Mohammadi Torbati, Banafsheh Golestan, Amir Hossein Miladipour, Abbas Basiri, Nasser Shakhssalim, Mahmoud Parvin |
المصدر: | Urology Journal, Vol 8, Iss 2, Pp 99-106 (2011) |
بيانات النشر: | Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, 2011. |
سنة النشر: | 2011 |
المجموعة: | LCC:Diseases of the genitourinary system. Urology |
مصطلحات موضوعية: | kidney calculi, risk factors, calcium oxalate, hypercalciuria, hyperoxaluria, Diseases of the genitourinary system. Urology, RC870-923 |
الوصف: | PURPOSE: To evaluate different urinary factors contributing to idiopathiccalcium stone disease for determining appropriate medical treatments.MATERIALS AND METHODS: Two 24-hour urine samples were collectedfrom 106 male recurrent idiopathic calcium stone formers and another 109randomly selected men as the control group matching for age.RESULTS: Cases had significantly higher mean urine oxalate, calcium, uricacid, and chloride in comparison with the healthy controls (P < .001).After necessary adjustment, only mean urine levels of oxalate and uricacid were higher in stone formers than those in controls. The mean valueof supersaturation for calcium oxalate was significantly higher in patientsthan the controls (P = .001); whereas supersaturation for calcium phosphateand uric acid did not reach statistical significe(P = .675 and P = .675,respectively). Hyperoxaluria and hypercalciuria were among the mostfrequent abnormalities. After categorizing urine parameter values into fourquartiles, the risk of stone formation was found to increase as the urinecalcium, oxalate, uric acid, chloride, and citrate rise. In contrast, the risk ofstone formation decreased with the increase of urine potassium.CONCLUSION: Oxalate seems to play the most important role as urinary stonerisk factor in our population followed by calcium and uric acid. In additionto the risk factors, it seems that supersaturation as the sum of all risk factorsprobably has a high predictive value. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1735-1308 1735-546X |
Relation: | http://www.urologyjournal.org/index.php/uj/article/view/1019/545; https://doaj.org/toc/1735-1308; https://doaj.org/toc/1735-546X |
URL الوصول: | https://doaj.org/article/25b64248fcdd45a5848dc84c8bfe44f2 |
رقم الأكسشن: | edsdoj.25b64248fcdd45a5848dc84c8bfe44f2 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 17351308 1735546X |
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