دورية أكاديمية
Comparative Study of Outcomes of COVID-19 Infection in Vaccinated and Unvaccinated Patients- A Retrospective Analysis
| العنوان: | Comparative Study of Outcomes of COVID-19 Infection in Vaccinated and Unvaccinated Patients- A Retrospective Analysis |
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| المؤلفون: | Bhaskar Kakarla, Swaroopa Deme, Sugunasree Aakula, Abhilash Naini, Radhika Soanker, Nageswara Rao Modugu, Raju YSN |
| المصدر: | Journal of Clinical and Diagnostic Research, Vol 17, Iss 1, Pp OC09-OC12 (2023) |
| بيانات النشر: | JCDR Research and Publications Private Limited, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | co-morbidities, coronavirus disease 2019 vaccination, mortality, oxygen requirement, serum ferritin, Medicine |
| الوصف: | Introduction: Vaccine development was the highest priority during the Coronavirus disease 2019 (COVID-19) pandemic. An ideal vaccine should decrease the risk of infection and reduce the incidence and severity of the disease. Risk of disease or infection following COVID-19 vaccination needs to be evaluated for its efficacy and effectiveness. Aim: To compare the severity of the disease, oxygen requirement, and mortality between vaccinated and unvaccinated COVID-19 patients. Materials and Methods: This retrospective study was done on the data of the patients who were admitted to Nizams Institute of Medical Sciences. All the admitted patients with COVID-19 disease, diagnosed by either Reverse Transcriptase Polymerase Chain Reaction (RTPCR) or rapid antigen detection method from April 2021 to October 2021, were included. Parameters recorded were: age, gender, co-morbidities, clinical staging as per institute protocol, vaccination status, oxygen requirement, the requirement of non invasive or invasive ventilation, inflammatory markers like C-Reactive Protein (CRP), ferritin, D dimer, Computed Tomography (CT) severity index, and outcomes. Results: The mean age of patients was 49.7±14.8 yrs in the unvaccinated group, and 52.75±16.2 yrs in the vaccinated group. Out of 175 patients, 102 (58.28 %) were unvaccinated. There were 25 (14.28%) deaths, of which 20 (80%) were unvaccinated and 5 (20%) were vaccinated. Oxygen requirement was more among the unvaccinated 73/96 (76.04%). High flow oxygen /mechanical ventilation requirement was higher in unvaccinated compared to vaccinated, 38 (76%) vs 12 (24%) respectively (p-value |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2249-782X 0973-709X |
| Relation: | https://www.jcdr.net/articles/PDF/17239/56184_CE(AD)_F(SHU)_PF1(PS_KM)_PN(KM).pdf; https://doaj.org/toc/2249-782X; https://doaj.org/toc/0973-709X |
| DOI: | 10.7860/JCDR/2023/56184.17239 |
| URL الوصول: | https://doaj.org/article/a26174069b1e48ff8171ae3ba6a8f507 |
| رقم الأكسشن: | edsdoj.26174069b1e48ff8171ae3ba6a8f507 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2249782X 0973709X |
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| DOI: | 10.7860/JCDR/2023/56184.17239 |