دورية أكاديمية
Differences in pregnancy and perinatal outcomes among symptomatic versus asymptomatic COVID-19-infected pregnant women: a systematic review and meta-analysis
العنوان: | Differences in pregnancy and perinatal outcomes among symptomatic versus asymptomatic COVID-19-infected pregnant women: a systematic review and meta-analysis |
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المؤلفون: | Durray Shahwar A. Khan, La-Raib Hamid, Anna Ali, Rehana A. Salam, Nadeem Zuberi, Zohra S. Lassi, Jai K. Das |
المصدر: | BMC Pregnancy and Childbirth, Vol 21, Iss 1, Pp 1-14 (2021) |
بيانات النشر: | BMC, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Gynecology and obstetrics |
مصطلحات موضوعية: | Coronavirus, SARS-CoV-2, COVID-19, Pregnancy, Pregnant women, Clinical presentation, Gynecology and obstetrics, RG1-991 |
الوصف: | Abstract Background There is dearth of information on COVID-19’s impact on pregnant women. However, literature reported trends of COVID-19 differ, depending on the presence of clinical features upon presentation. Objective This systematic review aimed to assess differences in risk factors, management, complications, and pregnancy and perinatal outcomes in symptomatic vs. asymptomatic pregnant women with confirmed SARS-CoV-2 infection. Methods A search was run on electronic databases to identify studies reporting COVID-19 in pregnancy. Meta-analysis was performed and odds ratios and mean difference with 95% confidence intervals were calculated using Review Manager 5.4. Review Prospero registration number CRD42020204662. Results We included ten articles reporting data from 3158 pregnancies; with 1900 symptomatic and 1258 asymptomatic pregnant women. There was no significant difference in the mean age, gestational age, and body mass index between the two groups. The meta-analysis suggested that pregnant women who were obese (OR:1.37;95%CI:1.15 to 1.62), hypertensive (OR:2.07;95%CI:1.38 to 3.10) or had a respiratory disorder (OR:1.64;95%CI:1.25 to 2.16), were more likely to be symptomatic when infected with SARS-CoV-2. Pregnant women with Black (OR:1.48;95%CI:1.19 to 1.85) or Asian (OR:1.64;95%CI:1.23 to 2.18) ethnicity were more likely to be symptomatic while those with White ethnicity (OR:0.63;95%CI:0.52 to 0.76) were more likely to be asymptomatic. Cesarean-section delivery (OR:1.40;95%CI:1.17 to 1.67) was more likely amongst symptomatic pregnant women. The mean birthweight(g) (MD:240.51;95%CI:188.42 to 293.51), was significantly lower, while the odds of low birthweight (OR:1.85;95%CI:1.06 to 3.24) and preterm birth ( |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1471-2393 12406694 |
Relation: | https://doaj.org/toc/1471-2393 |
DOI: | 10.1186/s12884-021-04250-1 |
URL الوصول: | https://doaj.org/article/262f131caf124066941f9fd7e025a4c5 |
رقم الأكسشن: | edsdoj.262f131caf124066941f9fd7e025a4c5 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14712393 12406694 |
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DOI: | 10.1186/s12884-021-04250-1 |