دورية أكاديمية
Macular Neovascularization Secondary to Subclinical Angioid Streaks in Age-Related Macular Degeneration: Treatment Response to Anti-VEGF at 2-Year Follow-up
العنوان: | Macular Neovascularization Secondary to Subclinical Angioid Streaks in Age-Related Macular Degeneration: Treatment Response to Anti-VEGF at 2-Year Follow-up |
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المؤلفون: | Riccardo Sacconi, Andrea Servillo, Federico Rissotto, Leonardo Bottazzi, Eliana Costanzo, Maria Sole Polito, Beatrice Tombolini, Mariacristina Parravano, Francesco Bandello, Giuseppe Querques |
المصدر: | Ophthalmology and Therapy, Vol 13, Iss 5, Pp 1211-1222 (2024) |
بيانات النشر: | Adis, Springer Healthcare, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Ophthalmology |
مصطلحات موضوعية: | Age-related macular degeneration, Angioid streaks, Biomarker, Macular neovascularization, Multimodal imaging, OCT, Ophthalmology, RE1-994 |
الوصف: | Abstract Introduction To characterize the response to antivascular endothelial growth factor (VEGF) treatment of macular neovascularization (MNV) secondary to age-related macular degeneration (AMD) with subclinical angioid streaks (AS) during a 2-year follow-up. Methods Retrospective, longitudinal, case-control, and multicentric study. Among a cohort of neovascular AMD population, we selected patients with subclinical AS and treatment-naïve MNV treated with anti-VEGF for a 2-year follow-up. An age- and sex-matched control group with treatment-naïve MNV secondary to AMD without subclinical AS was selected. Demographics and differences in treatment response (i.e., number of injections needed, anatomical and functional outcomes) between the two groups were analyzed. Results Among 102 eyes of 102 patients with neovascular AMD, 34 eyes of 34 patients (82 ± 6 years old) were included in the subclinical AS group, whereas 68 eyes of 68 patients (81 ± 6 years old, p = 0.342) in the control group. All eyes with subclinical AS presented RPD compared to 56% of eyes without subclinical AS (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2193-8245 2193-6528 |
Relation: | https://doaj.org/toc/2193-8245; https://doaj.org/toc/2193-6528 |
DOI: | 10.1007/s40123-024-00918-x |
URL الوصول: | https://doaj.org/article/26adc8c04b8e4c129cfd9123b0be03ab |
رقم الأكسشن: | edsdoj.26adc8c04b8e4c129cfd9123b0be03ab |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 21938245 21936528 |
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DOI: | 10.1007/s40123-024-00918-x |