دورية أكاديمية
Influence of Magnetic Field Strength on Intravoxel Incoherent Motion Parameters in Diffusion MRI of the Calf
| العنوان: | Influence of Magnetic Field Strength on Intravoxel Incoherent Motion Parameters in Diffusion MRI of the Calf |
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| المؤلفون: | Tamara Alice Bäuchle, Christoph Martin Stuprich, Martin Loh, Armin Michael Nagel, Michael Uder, Frederik Bernd Laun |
| المصدر: | Tomography, Vol 10, Iss 5, Pp 773-788 (2024) |
| بيانات النشر: | MDPI AG, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Computer applications to medicine. Medical informatics |
| مصطلحات موضوعية: | IVIM, diffusion, calf, perfusion, field strength, skeletal muscle, Computer applications to medicine. Medical informatics, R858-859.7 |
| الوصف: | Background: The purpose of this study was to investigate the dependence of Intravoxel Incoherent Motion (IVIM) parameters measured in the human calf on B0. Methods: Diffusion-weighted image data of eight healthy volunteers were acquired using five b-values (0–600 s/mm2) at rest and after muscle activation at 0.55 and 7 T. The musculus gastrocnemius mediale (GM, activated) was assessed. The perfusion fraction f and diffusion coefficient D were determined using segmented fits. The dependence on field strength was assessed using Student’s t-test for paired samples and the Wilcoxon signed-rank test. A biophysical model built on the three non-exchanging compartments of muscle, venous blood, and arterial blood was used to interpret the data using literature relaxation times. Results: The measured perfusion fraction of the GM was significantly lower at 7 T, both for the baseline measurement and after muscle activation. For 0.55 and 7 T, the mean f values were 7.59% and 3.63% at rest, and 14.03% and 6.92% after activation, respectively. The biophysical model estimations for the mean proton-density-weighted perfusion fraction were 3.37% and 6.50% for the non-activated and activated states, respectively. Conclusions: B0 may have a significant effect on the measured IVIM parameters. The blood relaxation times suggest that 7 T IVIM may be arterial-weighted whereas 0.55 T IVIM may exhibit an approximately equal weighting of arterial and venous blood. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2379-139X 2379-1381 |
| Relation: | https://www.mdpi.com/2379-139X/10/5/59; https://doaj.org/toc/2379-1381; https://doaj.org/toc/2379-139X |
| DOI: | 10.3390/tomography10050059 |
| URL الوصول: | https://doaj.org/article/2721faa250444929a1acba1104ba04e5 |
| رقم الأكسشن: | edsdoj.2721faa250444929a1acba1104ba04e5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2379139X 23791381 |
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| DOI: | 10.3390/tomography10050059 |