دورية أكاديمية
Urinary N-acetyl-beta-d-glucosaminidase levels in diabetic adults
العنوان: | Urinary N-acetyl-beta-d-glucosaminidase levels in diabetic adults |
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المؤلفون: | Eiya Bibiana Omozee, Enajit Ibiene Okaka, Andrew Efosa Edo, Leonard Fedinard Obika |
المصدر: | Journal of Laboratory Physicians, Vol 11, Iss 01, Pp 001-004 (2019) |
بيانات النشر: | Thieme Medical and Scientific Publishers Pvt. Ltd., 2019. |
سنة النشر: | 2019 |
المجموعة: | LCC:Medicine |
مصطلحات موضوعية: | creatinine clearance, diabetic nephropathy, microalbumin, n-acetyl-beta-d-glucosaminidase, Medicine |
الوصف: | Diabetes mellitus (DM) is known to be one of the most common causes of end-stage renal disease. The disease is usually not detected on time, because of the large functioning reserve of the kidney. Currently used markers (serum creatinine, creatinine clearance, urea, and electrolytes) remain relatively normal even when more than 50% of the renal nephron is not functioning. The aim of this study was to determine the level of urinary N-acetyl-beta-d-glucosaminidase (NAG) in diabetic adults in comparison with some currently used markers. A total of 56 diabetic patients between the ages of 23 and 63 were used for this study and 30 nondiabetic between the ages of 18 and 62 were used as control. The diabetic patients were classified into three groups based on how long they have been diagnosed: 5 years (25). Spot midstream urine samples were collected into sterile containers, and blood samples were collected into plain tubes. All the analyses were done spectrophotometrically. Creatinine clearance was calculated using the Cockcroft–Gault Equation. There was a significant increase (P < 0.01) in NAG values of 2–5 years and above 5 years and control. The urinary microalbumin concentration of controls was significantly different (P < 0.05) only with those who have had DM for |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0974-2727 0974-7826 |
Relation: | https://doaj.org/toc/0974-2727; https://doaj.org/toc/0974-7826 |
DOI: | 10.4103/JLP.JLP_164_17 |
URL الوصول: | https://doaj.org/article/a27b6d9715d2427d8470644841492b11 |
رقم الأكسشن: | edsdoj.27b6d9715d2427d8470644841492b11 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 09742727 09747826 |
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DOI: | 10.4103/JLP.JLP_164_17 |