دورية أكاديمية

Urinary N-acetyl-beta-d-glucosaminidase levels in diabetic adults

التفاصيل البيبلوغرافية
العنوان: Urinary N-acetyl-beta-d-glucosaminidase levels in diabetic adults
المؤلفون: Eiya Bibiana Omozee, Enajit Ibiene Okaka, Andrew Efosa Edo, Leonard Fedinard Obika
المصدر: Journal of Laboratory Physicians, Vol 11, Iss 01, Pp 001-004 (2019)
بيانات النشر: Thieme Medical and Scientific Publishers Pvt. Ltd., 2019.
سنة النشر: 2019
المجموعة: LCC:Medicine
مصطلحات موضوعية: creatinine clearance, diabetic nephropathy, microalbumin, n-acetyl-beta-d-glucosaminidase, Medicine
الوصف: Diabetes mellitus (DM) is known to be one of the most common causes of end-stage renal disease. The disease is usually not detected on time, because of the large functioning reserve of the kidney. Currently used markers (serum creatinine, creatinine clearance, urea, and electrolytes) remain relatively normal even when more than 50% of the renal nephron is not functioning. The aim of this study was to determine the level of urinary N-acetyl-beta-d-glucosaminidase (NAG) in diabetic adults in comparison with some currently used markers. A total of 56 diabetic patients between the ages of 23 and 63 were used for this study and 30 nondiabetic between the ages of 18 and 62 were used as control. The diabetic patients were classified into three groups based on how long they have been diagnosed: 5 years (25). Spot midstream urine samples were collected into sterile containers, and blood samples were collected into plain tubes. All the analyses were done spectrophotometrically. Creatinine clearance was calculated using the Cockcroft–Gault Equation. There was a significant increase (P < 0.01) in NAG values of 2–5 years and above 5 years and control. The urinary microalbumin concentration of controls was significantly different (P < 0.05) only with those who have had DM for
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0974-2727
0974-7826
Relation: https://doaj.org/toc/0974-2727; https://doaj.org/toc/0974-7826
DOI: 10.4103/JLP.JLP_164_17
URL الوصول: https://doaj.org/article/a27b6d9715d2427d8470644841492b11
رقم الأكسشن: edsdoj.27b6d9715d2427d8470644841492b11
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:09742727
09747826
DOI:10.4103/JLP.JLP_164_17