دورية أكاديمية
Cyanobacteria, Cyanotoxins, and Neurodegenerative Diseases: Dangerous Liaisons
| العنوان: | Cyanobacteria, Cyanotoxins, and Neurodegenerative Diseases: Dangerous Liaisons |
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| المؤلفون: | Paola Sini, Thi Bang Chau Dang, Milena Fais, Manuela Galioto, Bachisio Mario Padedda, Antonella Lugliè, Ciro Iaccarino, Claudia Crosio |
| المصدر: | International Journal of Molecular Sciences, Vol 22, Iss 16, p 8726 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | cyanobacteria, cyanotoxins, neurodegenerative diseases, ALS, Amyotrophic Lateral Sclerosis, PD, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | The prevalence of neurodegenerative disease (ND) is increasing, partly owing to extensions in lifespan, with a larger percentage of members living to an older age, but the ND aetiology and pathogenesis are not fully understood, and effective treatments are still lacking. Neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis are generally thought to progress as a consequence of genetic susceptibility and environmental influences. Up to now, several environmental triggers have been associated with NDs, and recent studies suggest that some cyanotoxins, produced by cyanobacteria and acting through a variety of molecular mechanisms, are highly neurotoxic, although their roles in neuropathy and particularly in NDs are still controversial. In this review, we summarize the most relevant and recent evidence that points at cyanotoxins as environmental triggers in NDs development. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/22/16/8726; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms22168726 |
| URL الوصول: | https://doaj.org/article/27fc82110f0645af85cae4651c1dc667 |
| رقم الأكسشن: | edsdoj.27fc82110f0645af85cae4651c1dc667 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
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| DOI: | 10.3390/ijms22168726 |