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Nour Shaheen,1 Abdelrahman Mohamed,1 Almoatazbellah Attalla,1 Rehab Adel Diab,2 Sarya Swed,3 Abdulqadir J Nashwan,4 Ala’ Abdala Rababah,5 Mahmoud Tarek Hefnawy,6 Youssef Soliman,7 Omar Ahmed Abdelwahab,2 Mariam Tarek Desouki,1 Abdulrhman Khaity,8 Ahmed Shaheen,1 Abdelraouf Ramadan,9 Mostafa Meshref10 1Alexandria Faculty of Medicine, Alexandria University, Alexandria, Egypt; 2Faculty of Medicine, Al-Azhar University, Cairo, Egypt, Medical Research Group of Egypt, Cairo, Egypt; 3Aleppo University, Faculty of Medicine, Aleppo, Syria; 4Hamad Medical Corporation, Doha, Qatar; 5Internal Medicine, King Hussein Medical Center, Amman, Jordan; 6Faculty of Medicine, Zagazig University, Egypt, Medical Research Group of Egypt, Cairo, Egypt; 7Faculty of Medicine, Assiut University, Assiut, Egypt; 8Faculty of Medicine, Elrazi University, Khartoum, Sudan; 9Faculty of Medicine, Helwan University, Cairo, Egypt; 10Neurology Department, Faculty of Medicine, Al-Azhar University, Cairo, EgyptCorrespondence: Abdulqadir J Nashwan, Hamad Medical Corporation, PO Box 3050, Doha, Qatar, Email anashwan@hamad.qaAbstract: With over 58 million cases and 6 million deaths by August 2022, the Coronavirus disease 2019 (COVID-19), causing severe acute respiratory syndrome coronavirus 2 (SARs-CoV-2), has had an insurmountable impact on the world’s population. This is one of the worst health crises since 1918’s influenza pandemic. There are four subvariants of Omicron; BA.1, BA.1.1, BA.2 and BA.3. As a result of new mutations in its spike protein, most of which occur in its receptor binding site, the Omicron variant appears to be more transmissible and less resistant to vaccination and antibody response. Understanding Omicron’s virology and mutations is essential to developing diagnostic and therapeutic methods. A thorough assessment of control measures, as well as timely adjustment of control measures, requires addressing such issues as re-infection risk, vaccine response, booster vaccine doses, and the increased rate of Omicron infections. This review article aims to look at the current information about the different types of SARs-CoV-2, focusing on the new subtype BA.2.75.Keywords: outbreak, Omicron, subvariant, BA.2.75, COVID-19 |
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