دورية أكاديمية
Particle detection and tracking with DNA
| العنوان: | Particle detection and tracking with DNA |
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| المؤلفون: | Ciaran A. J. O’Hare, Vassili G. Matsos, Joseph Newton, Karl Smith, Joel Hochstetter, Ravi Jaiswar, Wunna Kyaw, Aimee McNamara, Zdenka Kuncic, Sushma Nagaraja Grellscheid, Céline Bœhm |
| المصدر: | European Physical Journal C: Particles and Fields, Vol 82, Iss 4, Pp 1-22 (2022) |
| بيانات النشر: | SpringerOpen, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Astrophysics LCC:Nuclear and particle physics. Atomic energy. Radioactivity |
| مصطلحات موضوعية: | Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798 |
| الوصف: | Abstract We present the first proof-of-concept simulations of detectors using biomaterials to detect particle interactions. The essential idea behind a “DNA detector” involves the attachment of a forest of precisely-sequenced single or double-stranded nucleic acids from a thin holding layer made of a high-density material. Incoming particles break a series of strands along a roughly co-linear chain of interaction sites and the severed segments then fall to a collection area. Since the sequences of base pairs in nucleic acid molecules can be precisely amplified and measured using polymerase chain reaction (PCR), the original spatial position of each broken strand inside the detector can be reconstructed with nm precision. Motivated by the potential use as a low-energy directional particle tracker, we perform the first Monte Carlo simulations of particle interactions inside a DNA detector. We compare the track topology as a function of incoming direction, energy, and particle type for a range of ionising particles. While particle identification and energy reconstruction might be challenging without a significant scale-up, the excellent potential angular and spatial resolution ( $$\lesssim 25^\circ $$ ≲ 25 ∘ axial resolution for keV-scale particles and nm-scale track segments) are clear advantages of this concept. We conclude that a DNA detector could be a cost-effective, portable, and powerful new particle detection technology. We outline the outstanding experimental challenges, and suggest directions for future laboratory tests. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1434-6052 |
| Relation: | https://doaj.org/toc/1434-6052 |
| DOI: | 10.1140/epjc/s10052-022-10264-6 |
| URL الوصول: | https://doaj.org/article/292f516afeb2449aa09c445d3ad23930 |
| رقم الأكسشن: | edsdoj.292f516afeb2449aa09c445d3ad23930 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 14346052 |
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| DOI: | 10.1140/epjc/s10052-022-10264-6 |