دورية أكاديمية
A Strep A vaccine global demand and return on investment forecast to inform industry research and development prioritization
| العنوان: | A Strep A vaccine global demand and return on investment forecast to inform industry research and development prioritization |
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| المؤلفون: | Donald R. Walkinshaw, Meghan E. E. Wright, Marni Williams, Tanya M. F. Scarapicchia, Jean-Louis Excler, Ryan E. Wiley, Anne E. Mullin |
| المصدر: | npj Vaccines, Vol 8, Iss 1, Pp 1-13 (2023) |
| بيانات النشر: | Nature Portfolio, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Immunologic diseases. Allergy LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Abstract Investment in Strep A vaccine R&D is disproportionately low relative to the large burden of Strep A diseases globally. This study presents a novel Strep A vaccine global demand and financial forecast model with estimates of potential global demand and associated revenue and profits for a hypothetical Strep A vaccine as well as a net present value (NPV) analysis of return on capital investments required to develop the vaccine. A positive NPV was calculated for a variety of developer scenarios and target populations, including the global rollout of the vaccine in private and public markets by a multinational pharmaceutical corporation and a staged rollout by a developing country vaccine manufacturer for both infant and child populations. The results suggest there is a viable commercial market for a Strep A vaccine. It is hoped that this study will help to inform industry decision-making and drive increased prioritization of, and investment in, Strep A vaccine research and development. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2059-0105 |
| Relation: | https://doaj.org/toc/2059-0105 |
| DOI: | 10.1038/s41541-023-00690-2 |
| URL الوصول: | https://doaj.org/article/29de0370a15941758b629c34865b2983 |
| رقم الأكسشن: | edsdoj.29de0370a15941758b629c34865b2983 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20590105 |
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| DOI: | 10.1038/s41541-023-00690-2 |