دورية أكاديمية
Comparative Study of Oral Dexmedetomidine and Oral Midazolam on Postoperative Recovery Characteristics of Paediatric Patients after Sevoflurane Anaesthesia
العنوان: | Comparative Study of Oral Dexmedetomidine and Oral Midazolam on Postoperative Recovery Characteristics of Paediatric Patients after Sevoflurane Anaesthesia |
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المؤلفون: | Raghavendra Prasad Saya, Sonu Sesham, Arunalatha Paigeri Sappagu, Kailashnath Reddy, Chenna Reddy , Sunil Chiruvella |
المصدر: | RUHS Journal of Health Sciences (2024) |
بيانات النشر: | Sonali Sharma on behalf of Rajasthan University of Health Sciences, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Medicine |
مصطلحات موضوعية: | Dexmedetomidine, Emergence agitation, Mida zolam, Sevoflurane., Medicine |
الوصف: | Introduction: Emergence agitation (EA) and emergence delirium (ED) are common in paediatric patients after general anaesthesia with Sevoflurane. The present study aimed at comparing EA and ED in paediatric patients receiving either Dexmedetomidine or Midazolam pre-medication. Methodology: The present prospective randomized double blind study was carried out in a teaching hospital. A total of 180 paediatric patients aged between 2-12 years undergoing surgery under general anaesthesia with Sevoflurane were enrolled. Patients were divided into two groups, group A received oral Midazolam 0.5 mg/kg 45 minutes before induction and group B received oral Dexmedetomidine 4 mcg/kg 45 minutes before induction of anaesthesia. Vital parameters, incidence and severity of EA, and duration of stay in post anaesthesia care unit were recorded. Results: Mean arterial pressure (MAP) and heart rate (HR) were significantly less in group B. Incidence of EA was 35.5% in group A and 2.22% in group B (p-value≤ 0.0001). Severity of agitation was significantly less in group B (p value ≤ 0.0001). Conclusion: Oral Dexmedetomidine premedication provides better recovery and reduces the incidence and severity of EA in paediatric patients after Sevoflurane anaesthesia in comparison to oral Midazolam. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2456-8309 2582-3590 |
Relation: | https://ruhsjhs.in/articleDetails.php?artid=TWpjMw==; https://doaj.org/toc/2456-8309; https://doaj.org/toc/2582-3590 |
DOI: | 10.37821/ruhsjhs.9.1.2024.661 |
URL الوصول: | https://doaj.org/article/2a007262b9cb41a886c8afdbab20ef58 |
رقم الأكسشن: | edsdoj.2a007262b9cb41a886c8afdbab20ef58 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 24568309 25823590 |
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DOI: | 10.37821/ruhsjhs.9.1.2024.661 |