دورية أكاديمية
أعرض في EDS

Neurodevelopment of children exposed intra-uterus by Zika virus: A case series.

التفاصيل البيبلوغرافية
العنوان: Neurodevelopment of children exposed intra-uterus by Zika virus: A case series.
المؤلفون: Pedro Massaroni Peçanha, Saint Clair Gomes Junior, Sheila Moura Pone, Marcos Vinicius da Silva Pone, Zilton Vasconcelos, Andrea Zin, Renata Hydee Hasue Vilibor, Roozemeria Pereira Costa, Maria Dalva Barbosa Baker Meio, Karin Nielsen-Saines, Patricia Brasil, Elizabeth Brickley, Maria Elisabeth Lopes Moreira
المصدر: PLoS ONE, Vol 15, Iss 2, p e0229434 (2020)
بيانات النشر: Public Library of Science (PLoS), 2020.
سنة النشر: 2020
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: The main goal of this manuscript was to investigate the neurodevelopment of children exposed by Zika virus in the intrauterine period who are asymptomatic at birth. Newborns with documented Zika virus exposure during the intrauterine period who were asymptomatic at birth were followed in the first two years of life for neurodevelopment using Bayley III test. Children were classified as having normal or delayed neurodevelopment for age based on most recent Bayley III evaluation results. Eighty-four infants were included in the study. The first Bayley III evaluation was performed at a mean chronological age of 9.7±3.1 month; 13 children (15%) had a delay in one of the three domains, distributed as follow: 10 (12%) in the language domain and 3 (3.5%) in the motor domain. The most recent Bayley III evaluation was performed at a mean age 15.3±3.1 months; 42 children (50%) had a delay in one of the three domains: 4 (5%) in cognition, 31 (37%) in language, and 20 (24%) in motor performance. There were no statistical differences in Gender, Gestational Age, Birth Weight and Head Circurference at birth between children with normal and delayed neurodevelopment for age. A very high proportion of children exposed ZIKV during pregnancy who were asymptomatic at birth demonstrated a delay in neurodevelopment, mainly in the language domain, the first two years of life.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0229434
URL الوصول: https://doaj.org/article/2b31727e78484f8fbfcba62afd59a236
رقم الأكسشن: edsdoj.2b31727e78484f8fbfcba62afd59a236
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0229434