دورية أكاديمية
Dexamethasone and postoperative analgesia in minimally invasive thoracic surgery: a retrospective cohort study
العنوان: | Dexamethasone and postoperative analgesia in minimally invasive thoracic surgery: a retrospective cohort study |
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المؤلفون: | Marzia Umari, Giacomo Paluzzano, Matteo Stella, Valentina Carpanese, Giovanna Gallas, Caterina Peratoner, Giulia Colussi, Gaia Maria Baldo, Edoardo Moro, Umberto Lucangelo, Giorgio Berlot |
المصدر: | Journal of Anesthesia, Analgesia and Critical Care, Vol 1, Iss 1, Pp 1-6 (2021) |
بيانات النشر: | BMC, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Anesthesiology LCC:Medical emergencies. Critical care. Intensive care. First aid |
مصطلحات موضوعية: | Dexamethasone, Postoperative pain, Minimally invasive thoracic surgery, Multimodal analgesia, Anesthesiology, RD78.3-87.3, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9 |
الوصف: | Abstract Background Dexamethasone is commonly used for the prevention of postoperative nausea and vomiting (PONV), and recent reviews suggest a role for dexamethasone in postoperative analgesia. The aim of this study is to evaluate the efficacy of dexamethasone as an analgesic adjuvant in minimally invasive thoracic surgery. Primary outcome was morphine consumption 24 h after surgery; secondary outcomes were pain control, measured as numeric rating scale (NRS), glycemic changes, PONV, and surgical wound infection. Results We performed a retrospective cohort study considering 70 patients who underwent elective lobectomy, segmentectomy, or wedge resection surgery with a mini-thoracotomy approach or video-assisted thoracoscopic surgery (VATS). All patients received the same locoregional techniques and short-acting opioids during surgery; 46 patients received dexamethasone at induction. There were no significant differences in morphine consumption at 24 h (p = 0.09) and in postoperative pain scores. Nevertheless, a higher frequency of rescue therapy (p = 0.01) and a tendency for a higher attempted-PCA pushes count were observed in patients who did not receive dexamethasone. No cases of surgical wound infections were detected, and the incidence of PONV was similar in the two groups. Postoperative glycemia was transiently higher in the dexamethasone group (p = 0.004), but the need of hypoglycemic therapy was not significantly different. Conclusions Preoperative administration of dexamethasone did not cause a significant reduction in morphine consumption, but appears to be safe and plays a role in a multimodal anesthesia approach for patients undergoing elective minimally invasive thoracic surgery. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2731-3786 |
Relation: | https://doaj.org/toc/2731-3786 |
DOI: | 10.1186/s44158-021-00023-6 |
URL الوصول: | https://doaj.org/article/dc2bc882c0fe44228e6adadf3094e673 |
رقم الأكسشن: | edsdoj.2bc882c0fe44228e6adadf3094e673 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 27313786 |
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DOI: | 10.1186/s44158-021-00023-6 |