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The complete genome sequence of Thermoproteus tenax: a physiologically versatile member of the Crenarchaeota.

التفاصيل البيبلوغرافية
العنوان: The complete genome sequence of Thermoproteus tenax: a physiologically versatile member of the Crenarchaeota.
المؤلفون: Bettina Siebers, Melanie Zaparty, Guenter Raddatz, Britta Tjaden, Sonja-Verena Albers, Steve D Bell, Fabian Blombach, Arnulf Kletzin, Nikos Kyrpides, Christa Lanz, André Plagens, Markus Rampp, Andrea Rosinus, Mathias von Jan, Kira S Makarova, Hans-Peter Klenk, Stephan C Schuster, Reinhard Hensel
المصدر: PLoS ONE, Vol 6, Iss 10, p e24222 (2011)
بيانات النشر: Public Library of Science (PLoS), 2011.
سنة النشر: 2011
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Here, we report on the complete genome sequence of the hyperthermophilic Crenarchaeum Thermoproteus tenax (strain Kra1, DSM 2078(T)) a type strain of the crenarchaeotal order Thermoproteales. Its circular 1.84-megabase genome harbors no extrachromosomal elements and 2,051 open reading frames are identified, covering 90.6% of the complete sequence, which represents a high coding density. Derived from the gene content, T. tenax is a representative member of the Crenarchaeota. The organism is strictly anaerobic and sulfur-dependent with optimal growth at 86°C and pH 5.6. One particular feature is the great metabolic versatility, which is not accompanied by a distinct increase of genome size or information density as compared to other Crenarchaeota. T. tenax is able to grow chemolithoautotrophically (CO₂/H₂) as well as chemoorganoheterotrophically in presence of various organic substrates. All pathways for synthesizing the 20 proteinogenic amino acids are present. In addition, two presumably complete gene sets for NADH:quinone oxidoreductase (complex I) were identified in the genome and there is evidence that either NADH or reduced ferredoxin might serve as electron donor. Beside the typical archaeal A₀A₁-ATP synthase, a membrane-bound pyrophosphatase is found, which might contribute to energy conservation. Surprisingly, all genes required for dissimilatory sulfate reduction are present, which is confirmed by growth experiments. Mentionable is furthermore, the presence of two proteins (ParA family ATPase, actin-like protein) that might be involved in cell division in Thermoproteales, where the ESCRT system is absent, and of genes involved in genetic competence (DprA, ComF) that is so far unique within Archaea.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22003381/pdf/?tool=EBI; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0024222
URL الوصول: https://doaj.org/article/a2c6817abcfc49ba9ceff36d400762bb
رقم الأكسشن: edsdoj.2c6817abcfc49ba9ceff36d400762bb
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0024222