Potentiating hypoxic microenvironment for antibiotic activation by photodynamic therapy to combat bacterial biofilm infections

التفاصيل البيبلوغرافية
العنوان:	Potentiating hypoxic microenvironment for antibiotic activation by photodynamic therapy to combat bacterial biofilm infections
المؤلفون:	Weijun Xiu, Ling Wan, Kaili Yang, Xiao Li, Lihui Yuwen, Heng Dong, Yongbin Mou, Dongliang Yang, Lianhui Wang
المصدر:	Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
بيانات النشر:	Nature Portfolio, 2022.
سنة النشر:	2022
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Bacteria in biofilms present unique metabolic conditions that limit the traditional antibiotic treatment. Here, the authors show a photodynamic therapy-activated chemotherapy potentiating the hypoxia of biofilms of methicillin-resistant Staphylococcus aureus, by developing hyaluronic acid nanoparticles functionalized with chlorin e6 and metronidazole.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-022-31479-x
URL الوصول:	https://doaj.org/article/2da4c4c5af1b41bdbec596157c4aae76
رقم الأكسشن:	edsdoj.2da4c4c5af1b41bdbec596157c4aae76
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-022-31479-x