دورية أكاديمية
Is Positron Emission Tomography Reliable to PredictPost-Chemotherapy Retroperitoneal Lymph NodeInvolvement in Advanced Germ Cell Tumors of theTestis?
| العنوان: | Is Positron Emission Tomography Reliable to PredictPost-Chemotherapy Retroperitoneal Lymph NodeInvolvement in Advanced Germ Cell Tumors of theTestis? |
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| المؤلفون: | Ziya Akbulut, Abdullah Erdem Canda, Ali Fuat Atmaca, Alper Caglayan, Erem Asil, Mevlana Derya Balbay |
| المصدر: | Urology Journal, Vol 8, Iss 2, Pp 120-126 (2011) |
| بيانات النشر: | Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, 2011. |
| سنة النشر: | 2011 |
| المجموعة: | LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: | testicular neoplasms, lymph nodes, positron-emission tomography, sensitivity and specificity, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | PURPOSE: To evaluate if 18 fluorodeoxyglucose positron emission tomography(18FDG-PET) scan could identify post-chemotherapy retroperitoneal lymphnode (RPLN) involvement in advanced germ cell tumors of the testis.MATERIALS AND METHODS: Between January 2005 and January 2009, 16patients with advanced germ cell tumors of the testis underwent RPLNdissection (RPLND) following chemotherapy. Before RPLND, abdominalcomputed tomography (CT), magnetic resonance imaging (MRI), and18FDG-PET were performed in all the patients. Findings on 18FDG-PETwere compared with pathological evaluation of the removed lymphatic tissue.RESULTS: Both abdominal CT and MRI demonstrated retroperitonealmasses in all the patients following chemotherapy. Although PET did not demonstrate any activity in 8 patients, tumor was detected histopathologically.In 1 patient, 18FDG-PET demonstrated activity; however, no tumor wasdetected on pathology. Of the remaining 7 patients, 18FDG-PET findingswere concordant with the histopathological findings. No activity wasdetected in 2 patients with no tumors whereas all 5 patients harboring viabletumor cells showed positive 18FDG-PET activity. In our study, sensitivityand specificity of 18FDG-PET in detecting RPLN involvement were detectedto be 39% and 67%, respectively.CONCLUSION: 18FDG-PET imaging does not seem to be a reliable methodin detecting RPLN involvement in advanced germ cell tumors of the testisfollowing chemotherapy. Therefore, we neither recommend routine use of18FDG-PET scanning nor decide the treatment work-up by solely relying onthe 18FDG-PET findings in this patient group. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1735-1308 1735-546X |
| Relation: | http://www.urologyjournal.org/index.php/uj/article/view/1022/548; https://doaj.org/toc/1735-1308; https://doaj.org/toc/1735-546X |
| URL الوصول: | https://doaj.org/article/2de09ff3d4e4400093aa0cc42b66352f |
| رقم الأكسشن: | edsdoj.2de09ff3d4e4400093aa0cc42b66352f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17351308 1735546X |
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